Carbadox cannot be used in food-producing animals within the European Union following the adoption of Commission Regulation EC 2788/98/EC. Monitoring of the longest remaining residue--quinoxaline-2-carboxylic acid (QCA)--is the most effective way of enforcing the prohibition on its use. The study was under taken to determine if QCA could be passed from pig to pig following the exposure of unmedicated animals to housing that had previously contained medicated animals. Drug-withdrawal studies were also carried out on medicated animals. Distinction between treated animals and those exposed to QCA might be required by competent national authorities to determine whether a positive result for QCA in tissue is truly 'violative'. Comparison of the ratio concentrations of QCA in tissues and body fluids was made to determine if they could be used as criteria for discrimination between illegally treated animals and environmental contamination.
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quinoxaline-2-carboxylic acid (QCA);
Document Type: Research Article
Queen's University Belfast Department of Veterinary Science Belfast UK
Chemical Surveillance Department Veterinary Sciences Division Department of Agriculture and Rural Development Stormont Belfast BT4 3SD UK
Publication date: June 1, 2004
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