Skip to main content
padlock icon - secure page this page is secure

Prediction of acute toxicity of organophosphorus pesticides using topological indices

Buy Article:

$60.00 + tax (Refund Policy)

Topological indices were used in the prediction of the acute toxicity (intraperitoneal and oral LD50) of organophosphorus pesticides on rats. Models with six variables for the prediction of LD50-i.p. (r = 0.849, Q2 = 0.613) and eight variables for LD50-oral (r = 0.906, Q2 = 0.701) were selected. External group and cross-validation by use of leave-n-out tests were also performed in order to assess the stability and the prediction performance of the selected topological models.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics

Keywords: Acute toxicity; Multilinear regression; Organophosphorus pesticides; Topological descriptors

Document Type: Research Article

Affiliations: 1: Unidad de Investigación de Diseño de Fármacos y Conectividad Molecular, Departamento de Química Física, Facultad de Farmacia, Universitat de Valencia, Spain 2: Laboratorio de Entomología y Control de Plagas, Departamento de Zoología, Instituto Cavanilles de Biodiversidat y Biología Evolutiva, Universidad de Valencia, Spain

Publication date: December 1, 2007

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more