A fast, simple, low-cost and high-throughput multiresidue pesticide analysis method was developed and validated for 300 pesticides in herbal and fruit infusion samples based on modified QuEChERS (quick, easy, cheap, effective, rugged and safe) procedure combined with gas chromatography
coupled with tandem mass spectrometry method (GC-MS/MS). The objectives were to develop low cost GC-MS/MS method, validate the method in accordance to SANTE/11,813/2017 guidance document and application in routine. The results obtained using different GC and MS/MS parameters were evaluated
in order to develop quick, robust, accurate and effective multiresidue method. Total analysis time was 28 min with 0.6 µL injection volume. For accurate quantification, matrix-matched calibration (MMC) curves (in range of 10 µg/kg – 250 µg/kg) were
applied to compensate matrix effect. The limits of quantification (LOQ) were ranged between 0.06 µg/kg and 135 µg/kg, and for the majority of the pesticides the LOQ were below the regulatory maximum residue limits. Most recoveries at 10 µg/kg and 100 µg/kg
were in the range 70%–120% indicating satisfactory accuracy. The validated method was applied to commercial herbal and fruit infusion products detecting chlorpyriphos, DEET, tebuconazole, terbuthylazine, piperonyl butoxide, biphenyl, pendimethalin, pirimiphos-methyl and p,p’-DDE
in more than 100 samples from 1,466 so risk assessment on human health was calculated specially for those pesticides.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
gas chromatography - tandem mass spectrometry;
tea and herbal infusions
Document Type: Research Article
Analytical Instruments Department, Shimadzu d.o.o, ., Zagreb, Croatia
Faculty of Chemical Engineering and Technology, Department of Analytical Chemistry, University of Zagreb, Zagreb, Croatia
Laboratorij Quanta, Quanta d.o.o, Rakov Potok, Croatia
Catalan Institute for Water Research (ICRA), H2O Building, Scientific and Technological Park of the University of Girona, Girona, Spain
Publication date: September 2, 2018
More about this publication?