Skip to main content
padlock icon - secure page this page is secure

A new liquid chromatography–fluorescence method for determination of perfluorooctanesulphonyl fluoride upon derivatisation with 1-naphthol

Buy Article:

$61.00 + tax (Refund Policy)

Perfluorooctanesulphonyl fluoride (PFOSF), as a main precursor of perfluorooctanesulphonate (PFOS) that is ubiquitous in the environment, has been released to the environment with substantial quantity. Determination of PFOSF presents significant analytical challenges for using liquid chromatography with UV (LC–UV) and fluorescence detection (LC–FLD) due to the lack of chromophore in the molecular structure. In this study, a new method was developed by derivatising PFOSF with 1-naphthol to form 1-naphthylperfluorooctanesulphonate (NPFOS), which allowed rapid qualitative and quantitative analysis using LC–UV and LC–FLD. The derivatising product was confirmed from the analyses by proton nuclear magnetic resonance and quadrupole–time of flight mass spectrometry. The LC–FLD method demonstrated good linearity in the NPFOS concentration range from 20 pg µL−1 to 20 ng µL 1 with a correlation coefficient better than 0.999, with the instrument detection limit of 1.5 pg µL 1.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics

Keywords: LC–FLD; POPs; derivatisation; perfluorooctanesulphonyl fluoride

Document Type: Research Article

Affiliations: 1: State Key Laboratory of Environmental and Biological Analysis and Department of Chemistry, Hong Kong Baptist University, Hong Kong SAR, China 2: California Department of Public Health, Richmond, CA, 94804, USA

Publication date: December 8, 2014

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more