Skip to main content
padlock icon - secure page this page is secure

Bioaccumulation and biotransformation of 1-hydroxypyrene by the marine whelk Neptunea lyrata

Buy Article:

$61.00 + tax (Refund Policy)

In the marine environment, organisms can be exposed to oxidised forms of polycyclic aromatic hydrocarbons. Bioaccumulation and biotransformation of these derivatives has rarely been investigated and would lead to a better understanding of the overall fate of polycyclic aromatic hydrocarbons and that of other phenolic contaminants. The marine whelk Neptunea lyrata was exposed to 1-hydroxypyrene through its diet over 35 days. Extracts from the muscle and visceral mass of each animal were analysed by liquid chromatography with fluorescence detection. The quantified compounds included 1-hydroxpyrene and the phase II metabolites pyrene sulphate, pyrene glucuronide and one isomer of pyrenediol disulphate. The hydroxylated hydrocarbon was highly retained with 78% of the exposure amount recovered primarily from the visceral mass of the whelks, while the muscle accounted for 4% of the body burden. Whelks efficiently biotransformed 1-hydroxypyrene with a mean of 81% of the compound detected as phase II metabolites. The novel biotransformation product, pyrenediol disulphate, accounted for the largest proportion of the 1-hydroxypyrene derivatives detected at body burdens below 200 ng. At higher body burdens, bioaccumulation increased. Control animals showed trace levels of pyrene derivatives with 76% represented by metabolites. This study highlights the importance of investigating the multiple fates of reactive chemicals in order to interpret exposure.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics

Keywords: PAH; bioaccumulation; biotransformation; metabolite; pyrene; whelk

Document Type: Research Article

Affiliations: Ecosystem Research Division, Department of Fisheries and Oceans, DartmouthNova Scotia B2Y 4A2, Canada

Publication date: November 1, 2011

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more