Nickel versus copper: enhanced antibacterial activity in a series of new nickel(II) Schiff base complexes
Five new Ni(II) Schiff base complexes [NiLx(Solv)2] denoted by NiLx, x = 1–5, were synthesized and characterized. The Schiff base ligands were synthesized from the condensation of 5-bromo-2-hydroxy-3-nitrobenzaldehyde with different
aliphatic and aromatic diamines. The X-ray crystal structure of NiL3 was determined. The ligands and complexes were tested as antibacterial agents against two gram(+) and two gram(−) human pathogenic bacteria. The complexes showed moderate antibacterial activity against both
gram type bacteria. The new Ni(II) complexes showed enhanced antibacterial activity compared to the previously reported Cu(II) complexes of the same ligands.
Keywords: Schiff base; antibacterial; nickel(II) complexes
Document Type: Research Article
Affiliations: Department of Chemistry, Semnan University, Semnan, Iran
Publication date: 17 January 2016
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