Six-coordinate cadmium(II) complex containing a bridging dithiolate ligand: synthesis, crystal structure and antifungal activity study

A mixed-ligand polymeric metal complex of Cd(II) has been prepared by reactions of Cd(NO₃)₂·4H₂O with 1,3-diaminopropane (tn) and potassium salt of 1,1-dicyanoethylene-2,2-dithiolate and characterized on the basis of spectroscopy and single-crystal X-ray diffraction analysis. Single-crystal X-ray diffraction analysis reveals that the Cd(II) complex crystallizes in monoclinic space group P2 ₁ /n with distorted octahedral coordination geometry. The Cd(II) complex was screened in vitro against fungal pathogens such as Synchytrium endobioticum, Pyricularia oryzae, Helminthosporium oryzae, Candida albicans (ATCC10231), and Trichophyton mentagrophytes by the disk diffusion method. The biological testing data of the primary ligand K₂i-MNT·H₂O and [Cd(tn)(i-MNT)]_n indicate that the complex exhibits fungistatic antifungal activity, whereas K₂i-MNT·H₂O has no activity. The fungicidal properties of [Cd(tn)(i-MNT)]_n showed that the cadmium complex was more bioactive than the parent ligand.