Skip to main content
padlock icon - secure page this page is secure

Synthesis and DNA studies of a copper(II) complex of 5,6-dihydro-5,6-epoxy-1,10-phenanthroline

Buy Article:

$63.00 + tax (Refund Policy)

A new copper(II) complex, [Cu(epoxy)(phen)(NO3)](NO3)·H2O (epoxy = 5,6-dihydro-5,6-epoxy-1,10-phenanthroline, phen = 1,10-phenanthroline), has been synthesized and characterized by elemental analysis, IR and UV–vis spectroscopy, and single crystal X-ray diffraction. The complex crystallized in a monoclinic system with space group P21/n, a = 13.3199(8) Å, b = 11.2917(7) Å, c = 16.0832(9) Å, α = 90°, β = 107.827(4)°, and γ = 90°. The complex cation possesses a distorted octahedral geometry, with Jahn–Teller distortion occurring in the CuN4O2 core. The binding interaction with calf thymus DNA (CT–DNA) was investigated by UV–vis and fluorescence spectroscopy, cyclic voltammetry, and viscometry. The results support a partially intercalative binding mode. Efficient cleavage of plasmid DNA by the complex was observed by gel electrophoresis.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics

Keywords: DNA binding; DNA cleavage; Epoxy-phenanthroline; Fluorescence; Six-coordinate copper(II)

Document Type: Research Article

Affiliations: Department of Chemistry, Thiruvalluvar University, Vellore, India

Publication date: December 17, 2015

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more