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Two new daphnane diterpenes from the roots of Stelleropsis tianschanica

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Two new daphnane diterpenes named tianchaterpenes A and B were isolated from the roots of Stelleropsis tianschanica. Their structures were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR analyses and HRESIMS. Compounds 1 and 2 were evaluated for their cytotoxic activities against HeLa and HCT-8 cell lines. The results showed that all compounds displayed weak cytotoxicities to the HeLa cells and were inactive to the HCT-8 cells.

Keywords: S. tianschanica; Stelleropsis; daphnane diterpenes; tianchaterpene A; tianchaterpene B

Document Type: Research Article

Affiliations: 1: College of Chinese Medicinal Material, Jilin Agricultural University, Changchun, 130118, China 2: Department of Natural Medicinal Chemistry, Xinjiang Institute of Chinese and Ethnic Medicine, Urumqi, 830002, China

Publication date: 02 December 2018

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