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C18-Diterpenoid alkaloids from Delphinium anthriscifolium var. majus

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Five new C18-diterpenoid alkaloids, anthriscifoltines C-G (1–5), along with four known diterpenoid alkaloids anthriscifolcines C-F (6–9), were isolated from the extract of Delphinium anthriscifolium var. majus. Their structures were elucidated by extensive spectroscopic analyses (including 1D-, 2D-NMR, and HR-ESI-MS). Compounds 1–5 were also evaluated for their cytotoxic activity against MCF-7, HepG2, and H460 human cancer cell lines.

Keywords: C18-diterpenoid alkaloids; Delphinium; Ranunculaceae; anthriscifolium; cytotoxicity

Document Type: Research Article

Affiliations: School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China

Publication date: 04 May 2018

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