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New chlamydosporol derivatives from the endophytic fungus Fusarium sp. #001

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Two new chlamydosporol derivatives, fusarilactone A (1) and fusarilactone B (2), together with nine known compounds (311), have been isolated from the crude extract of endophytic fungus Fusarium sp. #001. The structures of new compounds 1 and 2 were elucidated on the basis of extensive spectroscopic methods. Compound 1 showed mild cytotoxicities against three tumor cell lines (SMMC-7721, A-549, and MCF-7).

Keywords: Eupatorium adenophorum; Fusarium sp; chlamydosporol derivatives; cytotoxicity; endophytic fungi

Document Type: Research Article

Affiliations: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China

Publication date: 04 May 2014

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