Two new antioxidant diarylheptanoids from the fruits of Alpinia oxyphylla
Two new diarylheptanoids, 1-(3′,5′-dihydroxy-4′-methoxyphenyl)-7-phenyl-3-heptanone (1) and 1-(2′,4′-dihydroxy-3′-methoxyphenyl)-7-(4″-methoxyphenyl)-3-heptanone (2), along with known diarylheptanoid yakuchinone A (3), and
five flavanoids, tectochrysin (4), chrysin (5), izalpinin (6), kaempferol 7, 4′-dimethyl ether (7), and kaempferide (8) were isolated from the fruits of Alpinia oxyphylla Miq. Their structures were determined by means of spectroscopic methods.
Antioxidant activities of all the isolated compounds were evaluated using a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Compounds 1–3 and 6–8 exhibited potent antioxidant activities in the DPPH assay.
Keywords: Alpinia oxyphylla; antioxidant; diarylheptanoid
Document Type: Research Article
Affiliations: 1: Department of Pharmacy, Yancheng Institute of Health Science, Yancheng, 224005, China 2: State Key Laboratory Incubation Base of Chinese Medicine and Molecular Pharmacology, Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Shenzhen, 518057, China 3: Institute of Medicinal Plant Development, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, 100094, China
Publication date: 01 October 2013
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