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Two new ent-3,4-seco-labdane diterpenoids from Callicarpa nudiflora

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Two new ent-3,4-seco-labdane diterpenoids, methylcallicarpate (1) and callicarpic acid (2), were isolated from the leaves of Callicarpa nudiflora Hook et Arn. Their structures and relative configurations were established by analysis of spectroscopic data. Their absolute configurations were assigned by the application of the CD technique for the first time among the ent-3,4-seco-labdane-type diterpenes.

Keywords: CD; Callicarpa nudiflora; callicarpic acid; ent-3,4-seco-labdane diterpenoid; methylcallicarpate

Document Type: Research Article

Affiliations: 1: Hainan Provincial Key Laboratory of R&D on Tropical Medicinal Plants, Hainan Medical College, Haikou,571199, China 2: Academy of South Medicine and Li Medicine of Hainan Province, Haikou,571199, China 3: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang,110016, China 4: Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao,266003, China

Publication date: 01 January 2013

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