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Gerardianin A, a new abietane diterpenoid from Isodon lophanthoides var. gerardianus

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A new abietane diterpenoid, gerardianin A (1), along with a known compound 6,7-dehydroroyleanone (2), has been isolated from the aerial parts of Isodon lophanthoides var. gerardianus [Bentham] H. Hara. The structure of 1 was determined on the basis of spectroscopic methods and X-ray single-crystal diffraction analysis.

Keywords: Isodon lophanthoides var. gerardianus; NO production inhibitory activity; diterpenoid; gerardianin A

Document Type: Research Article

Affiliations: 1: College of Chinese Traditional Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China 2: Instrumental Analysis of Research Center, Sun Yat-Sen University, Guangzhou, China 3: College of Pharmacy, Nihon University, Chiba, Japan

Publication date: 01 September 2008

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