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Poriacosones A and B: two new lanostane triterpenoids from Poria cocos

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Two new lanostane triterpenoids, poriacosones A (8) and B (9), together with eight known compounds were isolated from the sclerotia of Poria cocos (Schw.) Wolf (Polyporaceae), and identified by spectroscopic analysis, including IR, UV, CD, ESI-TOF-MS, HR-SIMS, 1D-, and 2D-NMR spectra. The structures of the new compounds were established as 3α,16α-dihydroxy-24-oxolanost-7,9(11)-dien-21-oic acid (8) and 3,16α-dihydroxy-24-oxolanost-7,9(11)-dien-21-oic acid (9).
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Keywords: Poria cocos; lanostane triterpenoids; poriacosone A; poriacosone B

Document Type: Research Article

Affiliations: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China

Publication date: July 1, 2008

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