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Two new pregnanes from Aglaia perviridis Hiern

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Two new pregnanes, 2α,3α,20-trihydroxy-16-acetoxy-20(R)-pregnane (1) and 2α,3α,15-trihydroxy-16-acetoxy-pregnane-20(R)-methacrylate (2), along with five known compounds, were isolated from the ethanolic extract of the twigs of Aglaia perviridis Hiern using chromatographic methods. The structures of 1 and 2 were elucidated on the basis of spectral data.
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Keywords: 2α,3α,15-trihydroxy-16-acetoxy-pregnane-20(R)-methacrylate; 2α,3α,20-trihydroxy-16-acetoxy-20(R)-pregnane; Aglaia perviridis Hiern; pregnane

Document Type: Research Article

Affiliations: 1: State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, CAS, Shanghai, China 2: Department of Clinical Pharmacology, General Hospital of Chinese, PLA, Beijing, China

Publication date: May 1, 2008

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