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Dammarane- and taraxastane-type triterpenoids from Saussurea oligantha Franch

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A new dammarane triterpenoid oliganthas A (1) and a new taraxastane triterpenoid oliganthas B (2), as well as five known taraxastane triterpenoids, ptiloepoxide (3), taraxast-20(30)ene-3,21α-diol (4), 22-oxo-20-taraxasten-3-ol (5), taraxast-20-ene-3,30-diol (6), and taraxastane-3,20α-diol (7), were isolated from the whole plant of Saussurea oligantha Franch. Their structures were elucidated by a series of spectroscopic methods. These compounds, especially taraxastanes 2, 5, and 6, exhibited significant antibacterial activity against Actinomyces viscosus ATCC27044.
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Keywords: Saussurea oligantha Franch; antibacteria; dammarane; taraxastane; triterpenoids

Document Type: Research Article

Affiliations: Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, China

Publication date: May 1, 2008

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