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Triterpenoid prosapogenols and prosapogenins from the husks of Xanthoceras sorbifolia

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Two new prosapogenins, 16-O-acetyl-21-O-(4-angeloyl)-α-l-rhamnopyranosyl barringtogenol C (1), 28-O--d-glucopyranosyl 16-deoxybarringtogenol C (2), were isolated from the acid hydrolyzate of the crude saponin obtained from the husks of Xanthoceras sorbifolia Bunge, along with six known triterpenoids. These structures were established on the basis of chemical and detailed spectral evidences. Compounds 1 and 2 showed cytotoxic activity against human cell lines (A375-S2, HeLa).
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Keywords: Cytotoxic activity; Prosapogenin; Prosapogenol; Sapindaceae; Xanthoceras sorbifolia

Document Type: Research Article

Affiliations: 1: Research Department of Natural Medicines, Shenyang Pharmaceutical University, Shenyang, China 2: School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China

Publication date: January 1, 2007

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