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Chemical constituents of the leaves of Diospyros kaki and their cytotoxic effects

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Isolation and structure elucidation of two new compounds, kakispyrone (1) and kakisaponin A (2), together with 11 known compounds, from the leaves of Diospyros kaki L. are described. Their cytotoxic effects against several cancer cell lines (A549, HepG2 and HT29) are also reported.
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Keywords: Cytotoxic effect; Diospyros kaki L; Kakisaponin A; Kakispyrone

Document Type: Research Article

Affiliations: 1: Department of Biological Science and Biotechnology, Beijing University of Chemical Technology, Beijing, China 2: Department of Natural Medicines, Shenyang Pharmaceutical University, Shenyang, China 3: Department of Biological Science and Biotechnology, Tsinghua University, Beijing, China

Publication date: January 1, 2007

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