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Home / Journal of Asian Natural Products Research, Volume 9, Number 3

A new nonadride derivative from mangrove fungus (strain No. k38)

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Authors: Li, C.-Y. 1 ; Yang, R.-Y. 2 ; Lin, Y.-C. 2 ; She, Z.-G. 2 ; Zhou, S.-N. 3 ; 

Source: Journal of Asian Natural Products Research, Volume 9, Number 3, April 2007, pp. 285-291(7)

Publisher: Taylor and Francis Ltd

DOI: https://doi.org/10.1080/10286020600727418

A new nonadride derivative, ( - )-1-hydroxybyssochlamic acid (1) and the known ( - )-byssochlamic acid (2) were isolated from mangrove fungus (strain No. k38) collected from the South China Sea coast. The structure and relative configuration of 1 were elucidated by spectral data and X-ray diffraction analysis. Primary bioassays showed that 2 had medium cytotoxic activity against HEp-2 and HepG2 Cells, and 1 exhibited weak activity.

Keywords: ( - )-1-Hydroxybyssochlamic acid; Cytotoxic; Fungus; X-ray diffraction

Document Type: Research Article

Affiliations: 1: College of Science, South China Agricultural University, Guangzhou, China 2: School of Chemistry and Chemical Engineering, Zhongshan University, Guangzhou, China 3: College of Life Science, Zhongshan University, Guangzhou, China

Publication date: 01 April 2007

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