Exposure to organic and inorganic traffic-related air pollutants alters haematological and biochemical indices in albino mice Mus musculus
The relationship between air pollution exposure and haematology remains controversial. Evidences in the effect of trace organic air pollutants and in the impact of such exposure on lipid and protein levels are scarce. This work investigated the health effects of medium-term exposure
to traffic-related air pollution on both haematological and biochemical indices in animal models. Two groups of albino mice (Mus musculus) were exposed to ambient air polluted by vehicle exhaust for three and six months, and one group was kept as control. Results found significant depletions
(p < 0.05) in red blood cells, packed cell volume, neutrophils, eosinophils, monocytes, and total cholesterol after air pollution exposure. On the contrary, significant elevations (p < 0.05) were observed in platelet, lymphocytes, and serum albumin compared
to control condition. Correlation data suggested that significant changes in blood parameters may be altered by the synergistic effect of several organic and inorganic air pollutants.
Keywords: Air pollution; animal exposure; biomarker; haematology; vehicular emission
Document Type: Research Article
Affiliations: Department of Studies in Environmental Science, University of Mysore, Mysore, India
Publication date: 03 March 2020
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