Acute effects of second-hand smoke on complete blood count
We assessed the acute effects of a 1-h exposure to second-hand smoke (SHS) on complete blood count (CBC) markers in a controlled simulated bar/restaurant environment. Nineteen adult never-smokers completed a 1-h .exposure to SHS at bar/restaurant levels, and a 1-h exposure to normal
room air. Blood samples were collected at the baseline at 30 min during each exposure, and at 0, 0.5, 1, 2, 3, and 4 h after each exposure. The values of white blood cells (WBC) at 1 h (p = 0.010), 3 h (p = 0.040), and 4 h
(p = 0.008) following SHS were significantly increased compared with the baseline values. Also, there was a positive association between the WBC and cotinine levels (r = 0.28, p = 0.007). A 1-h exposure to SHS at bar/restaurant
levels significantly increased the WBC for at least 4 h following the exposure time. This effect of SHS on WBC has dose–response characteristics and should be considered to prescribing CBC.
Keywords: environmental tobacco smoke; inflammation; passive smoking; white blood cells
Document Type: Research Article
Affiliations: 1: FAME Laboratory, Centre for Research and Technology Thessaly, Trikala, Greece. 2: School of Sport, Performing Arts and Leisure, University of Wolverhampton, Wolverhampton, UK. 3: Department of Exercise Sciences, University of Thessaly, Trikala, Greece. 4: Centre of Toxicology Science and Research, School of Medicine, University of Crete, Herakleio, Greece. 5: Harvard School of Public Health, Harvard University, Boston, USA.
Publication date: 02 January 2014
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