Cancer incidence and pattern of arsenic concentration in drinking water wells in Córdoba, Argentina
Cancer occurrence is associated with Arsenic (As) in drinking water. In Argentina, there are high As concentrations in groundwater but there is no published evidence yet of an association between geographic patterns of cancer incidence and the distribution of As in groundwater supplies.
The purpose of this study is to assess the association between cancer incidence patterns and As in Córdoba province's aquifers. Age standardized incidence rates (ASIRs) were obtained from Córdoba Cancer Registry (CCR), and As data from official reports of monitoring wells. A
multilevel model was applied. Total ASIRs by aquifers for males/females were 191.01/249.22 (Rioja plain); 215.03/225.37 (Pampa hills); and 239.42/188.93 (Chaco-Pampa plain). As was associated with increased risk of colon cancer in women, and lung and bladder cancers in both sexes. It had no
association with breast cancer. ASIRs were related to As, controlling for unobserved heterogeneity. An overlapping pattern of higher As and higher risks was evident for lung, bladder and female colon cancers.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
Document Type: Research Article
School of Nutrition, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Enrique Barros esq. Enfermera Gordillo, Ciudad Universitaria, Córdoba,5000, Argentina
CONICET and Departamento de Construcciones Civiles,Facultad de Ciencias Exactas, Físicas y Naturales, Universidad Nacional de Córdoba, Velez Sarsfield 1611, Ciudad Universitaria, Córdoba,5000, Argentina
CONICET and Instituto de Biologia Celular, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Enrique Barros esq. Enfermera Gordillo, Ciudad Universitaria, Córdoba,5000, Argentina
June 1, 2012
More about this publication?