Quantification of airway deposition of intact and fragmented pollens
Although pollen is one of the most widespread agents that can cause allergy, its airway transport and deposition is far from being fully explored. The objective of this study was to characterize the airway deposition of pollens and to contribute to the debate related to the increasing
number of asthma attacks registered after thunderstorms. For the quantification of the deposition of inhaled pollens in the airways computer simulations were performed. Our results demonstrated that smaller and fragmented pollens may penetrate into the thoracic airways and deposit there, supporting
the theory that fragmented pollen particles are responsible for the increasing incidence of asthma attacks following thunderstorms. Pollen deposition results also suggest that children are the most exposed to the allergic effects of pollens. Finally, pollens between 0.5 and 20 μm deposit
more efficiently in the lung of asthmatics than in the healthy lung, especially in the bronchial region.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
Monte Carlo simulations;
airway deposition of pollens;
Document Type: Research Article
Hungarian Academy of Sciences,KFKI Atomic Energy Research Institute, Budapest
Discipline of Physiology,University of Medicine and Pharmacy of Targu Mures, Targu Mures, Romania
Department of Materials Research and Physics, Division of Physics and Biophysics,University of Salzburg, Austria
Department of Laser Applications,Research Institute for Solid State Physics and Optics, Budapest
Medical School and Health Science Center,University of Debrecen, Hungary
December 1, 2011
More about this publication?