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Immunosuppressive Potential of Low Fat Buffalo Milk Supplemented with Omega-3 Fatty Acids

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The present investigation reports the evaluation of the immunosuppressive potential of low fat buffalo milk supplemented with omega-3 fatty acids in mice. The phagocytic activity of omega-3 milk group was 32% less than that of control group after 4 weeks and 42% less after 8 weeks of dietary regime. The lymphocyte proliferation index was 26% and 61% less than that of control after 4 and 8 weeks, respectively, when lipopolysaccharide was used as mitogen and 17.8% (4 weeks) and 19% (8 weeks) when concanavalin A was used as mitogen. The IgG level in serum reduced after dietary supplementation. IgG in intestine and IgA in intestine did not show any particular trend.
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Keywords: alpha linolenic acid; buffalo milk; docosahexaenoic acid; omega-3 fatty acids

Document Type: Research Article

Affiliations: 1: Kerala State Dairy Development Board, Kochi, Kerala, India 2: Dairy Technology Division, National Dairy Research Institute, Karnal, Haryana, –132001, India 3: Animal Biochemistry Division, National Dairy Research Institute, Karnal, Haryana, –132001, India

Publication date: July 4, 2015

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