Skip to main content
padlock icon - secure page this page is secure

Cytotoxic effect of four herbal medicines on gastric cancer (AGS) cell line

Buy Article:

$63.00 + tax (Refund Policy)

Gastric cancer (GC) is the fourth most common cancer and second leading cause of cancer-related death worldwide. Therefore, discovery of novel anti-cancer herbal drugs is of importance. Herbal medication is now being used for treatment of various diseases, including cancer in many countries. In this study, the cytotoxic effect of traditional herbal medicines (Aloe vera, Ginger, Ziziphora and Saffron extracts) was investigated on gastric AGS cell line. MTT assay was performed for cytotoxic effect of these herbal medicines. The most cytotoxic effects of Ginger, Ziziphora and Saffron extracts on AGS cell line were 47, 88 and 67%, respectively, compared to control group. According to our data, among these herbal extracts, Ziziphora has the highest cytotoxic effect on AGS cell line. Ziziphora extract seems to be a good candidate as an anti-cancer agent against GC. To clarify the effective molecules and their mechanisms, further studies are undertaken on animal models and humans.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics

Keywords: Aloe vera; Ginger; Saffron; Ziziphora; cytotoxic; gastric cancer (AGS)

Document Type: Research Article

Affiliations: 1: Immunoregulation Research Center,Shahed University, Tehran, Iran 2: Department of Immunology,Shahed University, Tehran, Iran 3: Department of Oncology and Hematology,Shahed University, Tehran, Iran 4: Department of Physiology,Shahed University, Tehran, Iran 5: Department of Biology,Shahed University, Tehran, Iran

Publication date: March 1, 2013

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more