Skip to main content
padlock icon - secure page this page is secure

Open Access Relationship between myocardial -adrenergic receptor characteristics and the incidence of ascites in broiler chickens

Download Article:
The present study was carried out to determine, first, the cardiac -adrenergic receptor characteristics of normal chickens and chickens with heart failure and, second, the characteristics of myocardial -adrenergic receptors in non-hypertrophied hearts in broilers exposed to two different altitude and temperature programmes. The density of -adrenergic receptors was significantly lower in myocardial cells in right ventricular failure birds compared with healthy birds. The binding capacity of -adrenergic receptors was reduced in the non-hypertrophied ventricles after exposure to high altitude in the younger but not in older chickens. At both altitudes, -adrenergic receptor binding capacity was not significantly different in low temperature compared with normal temperature birds. These data support the hypothesis of  -adrenergic receptor downregulation as one of the mechanisms of cardiac cell adaptation to hypertrophy or hypoxia. Second, the acclimatization to high altitude in older chickens resulted in a normalization of -receptor capacity in those broilers that were not affected by right ventricular failure and ascites.

20 References.

No Supplementary Data.
No Article Media
No Metrics

Document Type: Original Article

Affiliations: 1: Department of Poultry Diseases, Faculty of Veterinary Medicine, University of Tehran, P.O. Box 14155–6453, Tehran, Iran 2: Laboratory for Physiology and Immunology of Domestic Animals, K.U. Leuven, Kardinaal Mercierlaan 92, B– 3001 Heverlee, Belgium

Publication date: April 1, 2001

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more