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Free Content Micro reactors, flow reactors and continuous flow synthesis

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Dr Paul Watts is a reader in organic chemistry at The University of Hull and since graduating from the University of Bristol, where he completed a PhD in bio-organic natural product synthesis, he has led the Micro Reactor Group at Hull. In this role, he has published 90 papers, and he regularly contributes to the field by way of invited book chapters, review articles, and keynote lecturers on the subject of micro reaction technology in organic synthesis.

Dr Charlotte Wiles is the Chief Technology Officer at Chemtrix BV, and has been actively researching within the area of micro reaction technology for 10 years, starting with a PhD entitled Micro reactors in organic chemistry, which she obtained from The University of Hull in 2003. In the past decade, she has authored many scientific papers and review articles, recently co-authoring a book on the subject of micro reaction technology in organic synthesis. More recently, she has tailored her experience to the development and evaluation of commercially available continuous flow reactors, systems and peripheral equipment.

1. Introduction

2. Micro reactors

3. Meso and flow reactors

4. Flow processing in production

5. Conclusions

6. References

This review article explains the advantages of micro reactors and flow reactors as tools for conducting organic synthesis and describes how the technology may be used in research and development as well as production. A selection of examples is taken from the literature to illustrate how micro reactors enables chemists to perform their reactions more efficiently than when using batch processes.

49 References.

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Keywords: CONTINUOUS SYNTHESIS; ELECTROCHEMISTRY; FLOW REACTOR; MICRO REACTOR; PHOTOCHEMISTRY; PROCESS CHEMISTRY; SCALE-UP

Document Type: Review Article

Publication date: 01 April 2012

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  • The Journal of Chemical Research is a monthly journal which has a broad international authorship and publishes research papers and reviews in all branches of experimental chemistry.

    Established in 1977 as a joint venture by the British, French and German chemical societies it maintains the high standards set by the founding societies. Each paper is independently peer reviewed and only carefully evaluated contributions are accepted.

    Recent papers have described new synthetic methods, new heterocyclic compounds, new natural products, and the inorganic chemistry of metal complexes.

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