Molecular Medicine Reports

Research progress on the PI3K/AKT signaling pathway in gynecological cancer (Review)
pp. 4529-4535(7)
Authors: Shi, Xiang; Wang, Jingjing; Lei, Yu; Cong, Caofan; Tan, Dailin; Zhou, Xianrong

The 15dPGJ2 hydrogel ameliorates atopic dermatitis through suppression of the immune response
pp. 4536-4544(9)
Authors: Napimoga; ClementeNapimoga; Machabanski; Juliani; Acras; Macedo; Abdalla; de Pinho; Soares; Sperandio; de Araújo

Zinc finger Ebox binding homeobox 2 functions as an oncogene in human laryngeal squamous cell carcinoma
pp. 4545-4552(8)
Authors: Li; Ma; Wu; Wang; Huang; Shen; Yu

Alamandine attenuates longterm hypertensioninduced cardiac fibrosis independent of blood pressure
pp. 4553-4560(8)
Authors: Wang, Lan; Liu, Chi; Chen, Xiru; Li, Peng

MicroRNA1955p inhibitor prevents the development of osteoarthritis by targeting REGγ
pp. 4561-4568(8)
Authors: Shu; Long; Guo; Ye

Effects of granulocyte colonystimulating factor on rabbit carotid and porcine heart models of chronic obliterative arterial disease
pp. 4569-4578(10)
Authors: Hu; Chen; Wang; Jiang; Tse; Xu; Ge; Sun

YB1 protects cardiac myocytes against H2O2induced injury via suppression of PIAS3 mRNA and phosphorylation of STAT3
pp. 4579-4588(10)
Authors: Wang; He; Li; Hu; Huangfu; Chen

Quercetin suppresses glomerulosclerosis and TGFβ signaling in a rat model
pp. 4589-4596(8)
Authors: Liu; Dai; Yang

Decreased expression of ubiquilin1 following neonatal hypoxiaischemic brain injury in mice
pp. 4597-4602(6)
Authors: Luo; Liu; Tu; Ren; Zhao; Liu; Zhang; Chen; Zhang; Wang; Lü; Wang

Hypercholesterolaemia increases the risk of highturnover osteoporosis in men
pp. 4603-4612(10)
Authors: Zhou; Deng; Zhang; Guan; Zhao; Yu; Shao; Zhao; Xu

Long noncoding RNA STCAT16 suppresses cell growth and its expression predicts prognosis in patients with gastric cancer
pp. 4613-4622(10)
Authors: Zhang; Jiang; Zhang; Kuai; Mao; Wang

Proliferation of human hepatocellular carcinoma cells from surgically resected specimens under conditionally reprogrammed culture
pp. 4623-4630(8)
Authors: Wang; Bi; Song; Liu; Zheng; Wang; Shen

Prediction of IER5 structure and function using a bioinformatics approach
pp. 4631-4636(6)
Authors: Xiong; Jiang; Liu; Zhou; Ding

Arbutin promotes MC3T3E1 mouse osteoblast precursor cell proliferation and differentiation via the Wnt/βcatenin signaling pathway
pp. 4637-4644(8)
Authors: Man; Yang; Liu; Yang; Li; Fu

Lowintensity pulsed ultrasound promotes apoptosis and inhibits angiogenesis via p38 signalingmediated endoplasmic reticulum stress in human endothelial cells
pp. 4645-4654(10)
Authors: Su; Xu; Wang; Guo; Tu; Zhang; Kong; Sheng; Sun

MicroRNA1443p may participate in the pathogenesis of preeclampsia by targeting Cox2
pp. 4655-4662(8)
Authors: Hu; Li; Tong; Li; Chen; Lu; Wang; Min

lncRNA 430945 promotes the proliferation and migration of vascular smooth muscle cells via the ROR2/RhoA signaling pathway in atherosclerosis
pp. 4663-4672(10)
Authors: Cui; Wang; Shang; Li; Ma; Zhao; Song; Geng; Zhao; Tian; Wang

Effects of daphnetin on lipid metabolism, insulin resistance and oxidative stress in OAtreated HepG2 cells
pp. 4673-4684(12)
Authors: Liu; Liao; Chen; Han

Comprehensive analysis of differentially expressed profiles and reconstruction of a competing endogenous RNA network in papillary renal cell carcinoma
pp. 4685-4696(12)
Authors: Luo; Cui; Deng; Liu

Comprehensive analysis of the aberrantly expressed lncRNAassociated ceRNA network in breast cancer
pp. 4697-4710(14)
Authors: Tuersong; Li; Abulaiti; Feng

Novel variants in the KERA gene cause autosomal recessive cornea plana in a Chinese family: A case report
pp. 4711-4718(8)
Authors: Huang, Chengzi; Long, Xigui; Peng, Can; Lin, Pengsiyuan; Tan, Hu; Lv, Weigang; Wu, Lingqian

Effects of leukemia inhibitory factor receptor on the adipogenic differentiation of human bone marrow mesenchymal stem cells
pp. 4719-4726(8)
Authors: Wang; Yan; Xu; Yu; Wu; Yang; Li

Effect of integrin β1 in the treatment of stress urinary incontinence by electrical stimulation
pp. 4727-4734(8)
Authors: Li; Li; Liu; Hong; Min; Hu; Tang; Li; Wang; Zhou; Hong

Dysregulated long noncoding RNAs in pleomorphic adenoma tissues of pleomorphic adenoma gene 1 transgenic mice
pp. 4735-4742(8)
Authors: Xu; Liu; Lu; Fu; Zhang; Yang; Shen

Interleukin17A facilitates osteoclast differentiation and bone resorption via activation of autophagy in mouse bone marrow macrophages
pp. 4743-4752(10)
Authors: Song; Tan; Wang; Ding; Tang; Xia; Wei; Chen

Astaxanthin inhibits homocysteineinduced endothelial cell dysfunction via the regulation of the reactive oxygen speciesdependent VEGFVEGFR2FAK signaling pathway
pp. 4753-4760(8)
Authors: Wang; Tian; Wang; Zhang; Fan; Chen; Wang; Fu; Ma

Overexpression of CKS2 is associated with a poor prognosis and promotes cell proliferation and invasion in breast cancer
pp. 4761-4769(9)
Authors: Huang; Wu; Hong; Wang; Yang; Li

A novel resveratrol analog PA19 attenuates obesityinduced cardiac and renal injury by inhibiting inflammation and inflammatory cell infiltration
pp. 4770-4778(9)
Authors: Zhang; Chen; Sun; Wu; Bai; Liu; Shan; Liang; Zhang

miRNA15a5p facilitates the bone marrow stem cell apoptosis of femoral head necrosis through the Wnt/βcatenin/PPARγ signaling pathway
pp. 4779-4787(9)
Authors: Zhang; Chi; Meng; Liang

Novel agent #2714 potently inhibits lung cancer growth by suppressing cell proliferation and by inducing apoptosis in vitro and in vivo
pp. 4788-4796(9)
Authors: Lu; Sun; Chen; Li; Xu; Wang

Exosomes derived from mangiferinstimulated perivascular adipose tissue ameliorate endothelial dysfunction
pp. 4797-4805(9)
Authors: Zhao; Yang; Liu; Huang; Li

Signature microRNAs and long noncoding RNAs in laryngeal cancer recurrence identified using a competing endogenous RNA network
pp. 4806-4818(13)
Authors: Tang; Wei; Zhang; Xu

miR27b3p and miR607 cooperatively regulate BLM gene expression by directly targeting the 3'UTR in PC3 cells
pp. 4819-4831(13)
Authors: Chen; Zhao; Duan; Gong; Chen; Wang; Xu

Altered brain activity in patients with strabismus and amblyopia detected by analysis of regional homogeneity: A restingstate functional magnetic resonance imaging study
pp. 4832-4840(9)
Authors: Shao; Li; Li; Lin; Su; Shi; Zhu; Yuan; Shu; He; Liu; Ye

Triptolide inhibits migration and proliferation of fibroblasts from ileocolonic anastomosis of patients with Crohn's disease via regulating the miR161/HSP70 pathway
pp. 4841-4851(11)
Authors: Chen; Wang; Wang; Wu; Hou

Overexpression of COX6B1 protects against I/Rinduced neuronal injury in rat hippocampal neurons
pp. 4852-4862(11)
Authors: Yang; Wu; Xiao; Jiang

Caffeic acid phenethyl ester attenuates nuclear factorκBmediated inflammatory responses in Müller cells and protects against retinal ganglion cell death
pp. 4863-4871(9)
Authors: Jia; Jiang; Chen; Lu; Xie; Sun; Huang

Paroxysmal spasticity of lower extremities as the initial symptom in two siblings with maple syrup urine disease
pp. 4872-4880(9)
Authors: Liu; Chu; Liu; Sun; Kong; Li

High expression of DLC family proteins predicts better prognosis and inhibits tumor progression in NSCLC
pp. 4881-4889(9)
Authors: Sun; Sun; Song

Sulforaphane prevents PC12 cells from oxidative damage via the Nrf2 pathway
pp. 4890-4896(7)
Authors: Bao; Zhang; Chen; Wu; Xia; Chai; Yin

Endophilin 1 knockdown prevents synaptic dysfunction induced by oligomeric amyloid β
pp. 4897-4905(9)
Authors: Yin; Cha; Wu; Li; Li; Zhu; Zhang; Guo

Comprehensive genomic and prognostic analysis of the IL17 family genes in lung cancer
pp. 4906-4918(13)
Authors: Liao; Fan; Lv; Xu; Wu; Yang; Huang; Guo; Hu; Zhou; Duan; Wang; Jin

Transgelin 2 overexpression inhibits cervical cancer cell invasion and migration
pp. 4919-4926(8)
Authors: Zhou; Jiang; Yan; Dou

Role of lncRNA uc.457 in the differentiation and maturation of cardiomyocytes
pp. 4927-4934(8)
Authors: Zhang, Qijun; Cheng, Zijie; Yu, Zhangbin; Zhu, Chun; Qian, Lingmei

MicroRNA214 upregulates HIF1α and VEGF by targeting ING4 in lung cancer cells
pp. 4935-4945(11)
Authors: Li; Zhao; Qi; Yang

miR2103p regulates cell growth and affects cisplatin sensitivity in human ovarian cancer cells via targeting E2F3
pp. 4946-4954(9)
Authors: Jin, Yue; Wei, Jun; Xu, Shaoting; Guan, Fang; Yin, Lijun; Zhu, Haibin

Exogenous oestradiol benzoate induces male mice azoospermia through modulation of oxidative stress and testicular metabolic cooperation
pp. 4955-4963(9)
Authors: Le; Lei; Ren; Li; Tu; Ding; Yi; Zhou; Liu; Zhang

Salidroside suppresses the metastasis of hepatocellular carcinoma cells by inhibiting the activation of the Notch1 signaling pathway
pp. 4964-4972(9)
Authors: Lu; Liu; Dong; Xin

SIRT4 suppresses the PI3K/Akt/NFκB signaling pathway and attenuates HUVEC injury induced by oxLDL
pp. 4973-4979(7)
Authors: Tao; Yu; Chao; Wang; Xiong; Lai

Expression and potential regulation of miRNA431 during lung development of SpragueDawley rats
pp. 4980-4988(9)
Authors: Sun; Shen; Chen; Zhou; Cheng; Bao; Yang

Neuroprotective effects of lithium on a chronic MPTP mouse model of Parkinson's disease via regulation of αsynuclein methylation
pp. 4989-4997(9)
Authors: Zhao; Liu; Cheng; Zhu; Xiao; Bai; Tao

Long noncoding RNA PURPL promotes cell proliferation in liver cancer by regulating p53
pp. 4998-5006(9)
Authors: Fu, Xueyan; Wang, Yawei; Wu, Gang; Zhang, Wanchuan; Xu, Shaolin; Wang, Wenqing

(3R)5,6,7trihydroxy3isopropyl3methylisochroman1one attenuates cardiac dysfunction via the apelin/APJ signaling pathway
pp. 5007-5014(8)
Authors: Ding; Guan; Zhang; Yang; Yang

Acute exposure to 3deoxyglucosone at high glucose levels impairs insulin secretion from βcells by downregulating the sweet taste receptor signaling pathway
pp. 5015-5022(8)
Authors: Song; Liang; Shi; Zhou; Wang; Zhang; Huang; Jiang

Downregulation of DCC sensitizes multiple myeloma cells to bortezomib treatment
pp. 5023-5029(7)
Authors: RodriguesJunior; Biassi; de Albuquerque; Carlin; Buri; MachadoJunior; Vettore

Novel CLCN7 mutations cause autosomal dominant osteopetrosis type II and intermediate autosomal recessive osteopetrosis
pp. 5030-5038(9)
Authors: Li; Lv; Wang; Yue; Zhang

Combination of ions promotes cell migration via extracellular signalregulated kinase 1/2 signaling pathway in human gingival fibroblasts
pp. 5039-5045(7)
Authors: YamaguchiUeda; Akazawa; Kawarabayashi; Sugimoto; Nakagawa; Miyazaki; Kurogoushi; Iwata; Kitamura; Yamada; Hasegawa; Fukumoto; Iwamoto

Perspectives of small molecule inhibitors of activin receptorlike kinase in antitumor treatment and stem cell differentiation (Review)
pp. 5053-5062(10)
Authors: Cui; Shang; Lv; Zhao; Qi; Liu

Clinical significance of miRNA1 and its potential target gene network in lung squamous cell carcinoma
pp. 5063-5078(16)
Authors: Li; Qin; Huang; Ma; Hu

SM164 enhances the antitumor activity of adriamycin in human U2OS cells via downregulation of Xlinked inhibitor of apoptosis protein
pp. 5079-5086(8)
Authors: Chen, Jiangwei; Chen, Xuanyin; Chen, Xiaodong; Sun, Haiying; Yang, Dong

Inhibitory effect of 17βestradiol on triglyceride synthesis in skeletal muscle cells is dependent on ESR1 and not ESR2
pp. 5087-5096(10)
Authors: Liu; Li; Chen; Wang; Hu; Li; Zhu; Lu

CALB1 enhances the interaction between p53 and MDM2, and inhibits the senescence of ovarian cancer cells
pp. 5097-5104(8)
Authors: Cao; Wang; Liang; Pan

Pressure suppresses hepatocellular glycogen synthesis through activating the p53/Pten pathway
pp. 5105-5114(10)
Authors: Shen, Junwei; Sun, Yunchen; Shen, Si; Luo, Xu; Chen, Jie; Zhu, Liang

3,3'Diindolylmethane mitigates lipopolysaccharideinduced acute kidney injury in mice by inhibiting NOXmediated oxidative stress and the apoptosis of renal tubular epithelial cells
pp. 5115-5122(8)
Authors: He; Huang; Zhao

Human platelet lysate as an alternative to fetal bovine serum for culture and endothelial differentiation of human amniotic fluid mesenchymal stem cells
pp. 5123-5132(10)
Authors: Tancharoen, Waleephan; Aungsuchawan, Sirinda; Pothacharoen, Peraphan; Bumroongkit, Kanokkan; Puaninta, Chaniporn; Pangjaidee, Nathaporn; Narakornsak, Suteera; Markmee, Runchana; Laowanitwattana, Tanongsak; Thaojamnong, Chawapon

miR148 family members are putative biomarkers for sepsis
pp. 5133-5141(9)
Authors: Dong; Li; Zhang; Yang

Carbon monoxide releasing molecule2 (CORM2)liberated CO ameliorates acute pancreatitis
pp. 5142-5152(11)
Authors: Liu; Wang; Xu; Qin; Sun

MicroRNA195 triggers neuroinflammation in Parkinson's disease in a Rhoassociated kinase 1dependent manner
pp. 5153-5161(9)
Authors: Ren; Li; Xie; Wei; Liu

Curcumin reverses doxorubicin resistance via inhibition the efflux function of ABCB4 in doxorubicinresistant breast cancer cells
pp. 5162-5168(7)
Authors: Wen; Fu; Huang; Dai; Wang; Xu; Wu; Zhou

Effect of endoplasmic reticulum stress involved in manganeseinduced neurotoxicity in rats
pp. 5169-5176(8)
Authors: Wu; Yuan; Mo; Huang; Luo; Wang

Molecular hydrogen accelerates the reversal of acute obstructive cholangitisinduced liver dysfunction by restoring gap and tight junctions
pp. 5177-5184(8)
Authors: Zhu; Yu; Lin; Tang; Zhang; Lu

Effects of Paeoniflorin on the activity of muscle strips, intracellular calcium ion concentration and Ltype voltagesensitive calcium ion channels in the sphincter of Oddi of hypercholesterolemic rabbits
pp. 5185-5194(10)
Authors: Wang; Yang; Ji; Tao; Wang; Wang

MicroRNA93 regulates angiogenesis in peripheral arterial disease by targeting CDKN1A
pp. 5195-5202(8)
Authors: Shu; Mao; Li; Wang; Chang; Liu; Li

MicroRNA4865p inhibits the growth of human hypertrophic scar fibroblasts by regulating Smad2 expression
pp. 5203-5210(8)
Authors: Shi, Yingying; Wang, Luping; Yu, Pijun; Liu, Yi; Chen, Wei

Role of autophagy in LPSinduced inflammation in INS1 cells
pp. 5211-5218(8)
Authors: Zhu; Cao; Wang; Su; Jiang; Liu; Li

Role of feline sarcomarelated protein in the viability and apoptosis of bladder cancer cells
pp. 5219-5226(8)
Authors: Hu; Guo; Xu; Mei; Bi; Jiang; Yu; Zhong

miR125bmediated regulation of cell proliferation through the Jagged1/Notch signaling pathway by inhibiting BRD4 expression in psoriasis
pp. 5227-5236(10)
Authors: Pan; Huang; Zhu; Lin; Luo

A five lncRNA signature for prognosis prediction in hepatocellular carcinoma
pp. 5237-5250(14)
Authors: Sun; Zhang; Wang; Song; Jing; Zhang; Yu; Liu

Trichostatin Ainduced miR30a5p regulates apoptosis and proliferation of keloid fibroblasts via targeting BCL2
pp. 5251-5262(12)
Authors: Jian; Qu; Wang; Zou; Zhao; Chen; Gao; Chen; He

Screening of underlying genetic biomarkers for ankylosing spondylitis
pp. 5263-5274(12)
Authors: Fan; Qi; Ma; Ma

LINC01638 silencing inhibits cancer cell proliferation in colorectal adenocarcinoma through interaction with RUNX2
pp. 5275-5280(6)
Authors: Zhuo, Wenying; Hu, Dengdi; Chen, Xihua; Zhang, Tian

Identification of timeseries differentially expressed genes and pathways associated with heart failure postmyocardial infarction using integrated bioinformatics analysis
pp. 5281-5290(10)
Authors: Li; Li; Jiang

Vorapaxar stabilizes permeability of the endothelial barrier under cholesterol stimulation via the AKT/JNK and NFκB signaling pathways
pp. 5291-5300(10)
Authors: Pang; Hu; Wang; Jiang; Lai

Downregulation of miR186 promotes the proliferation and drug resistance of glioblastoma cells by targeting Twist1
pp. 5301-5308(8)
Authors: Xiong, Yifeng; Chen, Rensheng; Wang, Lizhen; Wang, Shanshan; Tu, Yi; Zhu, Lei; Wang, Chunliang

Bioinformatics identification of lncRNA biomarkers associated with the progression of esophageal squamous cell carcinoma
pp. 5309-5320(12)
Authors: Yu, Jun; Wu, Xiaoliu; Huang, Kaidan; Zhu, Ming; Zhang, Xiaomei; Zhang, Yuanying; Chen, Senqing; Xu, Xinyu; Zhang, Qin

High hydrostatic pressure induces apoptosis of retinal ganglion cells via regulation of the NGF signalling pathway
pp. 5321-5334(14)
Authors: Liu, Hongji; Wang, Wei; Li, Xiang; Huang, Chao; Zhang, Zongduan; Yuan, Mingyue; Li, Xiangyu

Downregulation of microRNA199a5p attenuates hypoxia/reoxygenationinduced cytotoxicity in cardiomyocytes by targeting the HIF1αGSK3βmPTP axis
pp. 5335-5344(10)
Authors: Liu; Zhang; Hu; Zhang; Cui

miR216a exacerbates TGFβinduced myofibroblast transdifferentiation via PTEN/AKT signaling
pp. 5345-5352(8)
Authors: Qu; Liu; Ye; Wang; Liu; Zhou; Wu; Lin; Shi; Yang

A heterozygous deficiency in protein phosphatase Ppm1b results in an altered ovulation number in mice
pp. 5353-5360(8)
Authors: Ishii; Homma; Watanabe; Kimura; Ohnishi; Kobayashi; Fujii

Genetic variant in the promoter region of microRNA137 reduces the warfarin maintenance dose in patients with atrial fibrillation
pp. 5361-5367(7)
Authors: Tian, Zhen; Yang, Yushuang; Feng, Zhaohui; Wu, Donghui; Yang, Wei; Liu, Dongna

Potential use of Pichia pastoris strain SMD1168H expressing DNA topoisomerase I in the screening of potential antibreast cancer agents
pp. 5368-5376(9)
Authors: Xin; Wan Mahtar; Siah; Miswan; Khoo

Salmonella infection leads to severe intestinal inflammation and increased CD4+FoxP3+ Treg cells in streptozotocininduced hyperglycemic mice
pp. 5377-5385(9)
Authors: Zhang; Wang; Wang; Li; Tang; Li

Chronic stress augments esophageal inflammation, and alters the expression of transient receptor potential vanilloid 1 and proteaseactivated receptor 2 in a murine model
pp. 5386-5396(11)
Authors: Wulamu; Yisireyili; Aili; Takeshita; Alimujiang; Aipire; Li; Jiang; Aizezi; Li; Abudureyimu

Long noncoding RNA NORAD promotes cell proliferation and glycolysis in nonsmall cell lung cancer by acting as a sponge for miR1365p
pp. 5397-5405(9)
Authors: Gao, Wei; Weng, Ting; Wang, Lifang; Shi, Bin; Meng, Wenshu; Wang, Xiaoyu; Wu, Ying; Jin, Liang; Fei, Lijuan

Identification of a long noncoding RNA signature to predict outcomes of glioblastoma
pp. 5406-5416(11)
Authors: Li; Lu; Li; Qi; Yu

Avicularin ameliorates human hepatocellular carcinoma via the regulation of NFκB/COX2/PPARγ activities
pp. 5417-5423(7)
Authors: Wang; Li; Quan; Shen

Ghrelin regulates sepsisinduced rat acute gastric injury
pp. 5424-5432(9)
Authors: Li; Lin; Guo; Liu; Li

Increased expression of the P2X7 receptor in temporal lobe epilepsy: Animal models and clinical evidence
pp. 5433-5439(7)
Authors: Song, Penghui; Hu, Jing; Liu, Xijin; Deng, Xuejun

Berberine improves advanced glycation end productsinduced osteogenic differentiation responses in human periodontal ligament stem cells through the canonical Wnt/βcatenin pathway
pp. 5440-5452(13)
Authors: Zhang; Wang; Wang; Li; Xu; Zhang

CD47 deficiency protects cardiomyocytes against hypoxia/reoxygenation injury by rescuing autophagic clearance
pp. 5453-5463(11)
Authors: Li; Zhao; Zong; Fu; Zheng; Bao; Yin; Chen; Lu; Dai; Hou; Kong

Changes in mitochondrial cytochrome c oxidase mRNA levels with cataract severity in lens epithelia of Japanese patients
pp. 5464-5472(9)
Authors: Nagai, Noriaki; Mano, Yu; Otake, Hiroko; Shibata, Teppei; Kubo, Eri; Sasaki, Hiroshi