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Home / International Journal of Oncology, Volume 45, Number 4
The International Journal of Oncology provides an international forum for the publication of the latest, cutting-edge research in the broad area of oncology and cancer treatment. The journal accepts original high quality works and reviews on all aspects of oncology research including carcinogenesis, metastasis, epidemiology, chemotherapy and viral oncology. Through fair and efficient peer review, the journal is dedicated to publishing top tier research in the field, offering authors rapid publication as well as high standards of copy-editing and production. The International Journal of Oncology is published on a monthly basis in both print and early online.

Publisher: Spandidos Publications

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Volume 45, Number 4, 2014

Articles

Redox-directed cancer therapeutics: Taurolidine and Piperlongumine as broadly effective antineoplastic agents (Review)
pp. 1329-1336(8)
Authors: Möhler; Pfirrmann; Frei

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Evolving therapeutic concepts in prostate cancer based on genome-wide analyses (Review)
pp. 1337-1344(8)
Authors: Georgi; Korzeniewski; Hadaschik; Grüllich; Roth; Sültmann; Pahernik; Hohenfellner; Duensing

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Clinical impact of the Warburg effect in gastrointestinal cancer (Review)
pp. 1345-1354(10)
Authors: Sawayama; Ishimoto; Sugihara; Miyanari; Miyamoto; Baba; Yoshida; Baba

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Roles of the calcium sensing receptor in digestive physiology and pathophysiology (Review)
pp. 1355-1362(8)
Authors: Xie; Tang; Yong; Luo; Yang

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TGF-β/Smad signaling during hepatic fibro-carcinogenesis (Review)
pp. 1363-1371(9)
Authors: Yoshida; Murata; Yamaguchi; Matsuzaki

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A subset of bone marrow stromal cells regulate ATP-binding cassette gene expression via insulin-like growth factor-I in a leukemia cell line
pp. 1372-1380(9)
Authors: Benabbou; Mirshahi; Bordu; Faussat; Tang; Therwath; Soria; Marie; Mirshahi

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A novel system for predicting the toxicity of irinotecan based on statistical pattern recognition with UGT1A genotypes
pp. 1381-1390(10)
Authors: Tsunedomi; Hazama; Fujita; Okayama; Kanekiyo; Inoue; Yoshino; Yamasaki; Suehiro; Oba; Mishima; Sakamoto; Hamamoto; Oka

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Sulforaphane, quercetin and catechins complement each other in elimination of advanced pancreatic cancer by miR-let-7 induction and K-ras inhibition
pp. 1391-1400(10)
Authors: Appari; Babu; Kaczorowski; Gross; Herr

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Motility of select ovarian cancer cell lines: Effect of extra­cellular matrix proteins and the involvement of PAK2
pp. 1401-1411(11)
Authors: Flate; Stalvey

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A novel cancer vaccine strategy with combined IL-18 and HSV-TK gene therapy driven by the hTERT promoter in a murine colorectal cancer model
pp. 1412-1420(9)
Authors: Higashi; Hazama; Araki; Yoshimura; Iizuka; Yoshino; Noma; Oka

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Preclinical antitumor activity of SST0116CL1: A novel heat shock protein 90 inhibitor
pp. 1421-1429(9)
Authors: Vesci; Milazzo; Carollo; Pace; Giannini

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Hypoxia induces resistance to ALK inhibitors in the H3122 non-small cell lung cancer cell line with an ALK rearrangement via epithelial-mesenchymal transition
pp. 1430-1436(7)
Authors: Kogita; Togashi; Hayashi; Sogabe; Terashima; De Velasco; Sakai; Fujita; Tomida; Takeyama; Okuno; Nakagawa; Nishio

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microRNA-194 suppresses osteosarcoma cell proliferation and metastasis in vitro and in vivo by targeting CDH2 and IGF1R
pp. 1437-1449(13)
Authors: Han; Zhao; Chen; Bian; Yang; Ma; Cai; Fan; Zhou; Ma

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Genetic screen identifies suppressor of morphogenesis in genitalia-1 (SMG-1) as a modulator of sorafenib resistance in hepatocellular carcinoma cell lines
pp. 1450-1456(7)
Authors: Nam; Park; Yang; Lee; Kim

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ISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer models
pp. 1457-1468(12)
Authors: Ioannou; Cheng; Crichlow; Birmpilis; Lolis; Tsitsilonis; Al-Abed

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Bortezomib prevents oncogenesis and bone metastasis of prostate cancer by inhibiting WWP1, Smurf1 and Smurf2
pp. 1469-1478(10)
Authors: Wang; Wang; Li; Xing; Ding; Shi; Zhang; Guo; Shu; Shan

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Cancer-associated fibroblasts from invasive breast cancer have an attenuated capacity to secrete collagens
pp. 1479-1488(10)
Authors: Fu; Song; Li; Yi; Chen; Ruan; Shi; Xu; Fu; Zheng

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Expression of the Bcl-2 family genes and complexes involved in the mitochondrial transport in prostate cancer cells
pp. 1489-1496(8)
Authors: Asmarinah; Paradowska-Dogan; Kodariah; Tanuhardja; Waliszewski; Mochtar; Budiningsih; Weidner; Hinsch

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Sulforaphane induces apoptosis in T24 human urinary bladder cancer cells through a reactive oxygen species-mediated mitochondrial pathway: The involvement of endoplasmic reticulum stress and the Nrf2 signaling pathway
pp. 1497-1506(10)
Authors: Jo; Kim; Kim; Park; Choi

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KLF5 promotes hypoxia-induced survival and inhibits apoptosis in non-small cell lung cancer cells via HIF-1α
pp. 1507-1514(8)
Authors: Li; Liu; Xu; Liu; Xie; Ni; Chen

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Ezrin is required for epithelial-mesenchymal transition induced by TGF-β1 in A549 cells
pp. 1515-1522(8)
Authors: Chen; Gao; Xu; Liu; Liu; Liu

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Histone deacetylase 3 promotes pancreatic cancer cell proliferation, invasion and increases drug-resistance through histone modification of P27, P53 and Bax
pp. 1523-1530(8)
Authors: Jiao; Hu; Yuan; Jin; Guo; Wang; Wang

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18F-FDG PET/CT can be used to detect non-functioning pancreatic neuroendocrine tumors
pp. 1531-1536(6)
Authors: Luo; Liu; Guo; Jin; Xiao; Liu; Xu; Zhang; Liu; Huang; Hu; Ni; Long; Yu

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miR222 regulates sorafenib resistance and enhance tumorigenicity in hepatocellular carcinoma
pp. 1537-1546(10)
Authors: Liu; Liu; Zhang; Ji; Wang; Liu

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Increased CDC20 expression is associated with development and progression of hepatocellular carcinoma
pp. 1547-1555(9)
Authors: Li; Gao; Du; Huang; Wei

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An oligonucleotide-tagged microarray for routine diagnostics of colon cancer by genotyping KRAS mutations
pp. 1556-1564(9)
Authors: Liu; Gudnason; Li; Bang; Wolff

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Therapeutic potential of capillary morphogenesis gene 2 extracellular vWA domain in tumourrelated angiogenesis
pp. 1565-1573(9)
Authors: Ye; Sun; Sanders; Martin; Lane; Mason; Jiang

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BTG1 expression in thyroid carcinoma: Diagnostic indicator and prognostic marker
pp. 1574-1582(9)
Authors: Lu; Sun; Liu; Yang; Cheng

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Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity
pp. 1583-1593(11)
Authors: Nakata; Tanaka; Ito; Hara; Fujita; Kondo; Kanemitsu; Yatabe; Nakanishi

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USP22 promotes the G1/S phase transition by upregulating FoxM1 expression via β-catenin nuclear localization and is associated with poor prognosis in stage II pancreatic ductal adenocarcinoma
pp. 1594-1608(15)
Authors: Ning; Wang; Liang; Xie; Liu; Feng; Yan; Wang

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Inhibition of activated Ras suppresses multiple oncogenic Hub genes in human epithelial tumors
pp. 1609-1617(9)
Authors: Cao; Wang; Luo; Wang; Wang; Zhang; Wang; Yao; Liu; You

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Altered microRNA expression profiles are involved in resistance to low-dose ionizing radiation in the absence of BMI1 in human dermal fibroblasts
pp. 1618-1628(11)
Authors: Bae; Kim; Cha; Choi; Shin; An; Lee; Song; Yang; Nam; An

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Morin, a flavonoid from Moraceae, suppresses growth and invasion of the highly metastatic breast cancer cell line MDA-MB231 partly through suppression of the Akt pathway
pp. 1629-1637(9)
Authors: Jin; Lee; Eun; Jung; Park; Kim; Choi; Ryu; Jung; Hong; Shin; Kim

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Notch1 promotes hepatitis B virus X protein-induced hepatocarcinogenesis via Wnt/β-catenin pathway
pp. 1638-1648(11)
Authors: Sun; Wang; Luo; Wang; Xiong; Liu; Cheng

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Silencing of CXCR7 gene represses growth and invasion and induces apoptosis in colorectal cancer through ERK and β-arrestin pathways
pp. 1649-1657(9)
Authors: Li; Zheng; Huang; Shi; Peng; Liang; Cai

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The neurokinin-1 receptor antagonist aprepitant is a promising candidate for the treatment of breast cancer
pp. 1658-1672(15)
Authors: Muñoz; González-Ortega; Salinas-Martín; Carranza; Garcia-Recio; Almendro; Coveñas

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Torilis japonica extract, a new potential EMT suppressor agent by regulation of EGFR signaling pathways
pp. 1673-1679(7)
Authors: Kim; Lee; Kim

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BAI, a novel Cdk inhibitor, enhances farnesyltransferase inhibitor LB42708-mediated apoptosis in renal carcinoma cells through the downregulation of Bcl-2 and c-FLIP (L)
pp. 1680-1690(11)
Authors: Jang; Cho; Kim; Lee; Lee; Kim; Park; Jang; Kim; Kwon; Park

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Auranofin displays anticancer activity against ovarian cancer cells through FOXO3 activation independent of p53
pp. 1691-1698(8)
Authors: Park; Lee; Berek; Hu

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The cytoplasmic domain of N-cadherin modulates MMP9 induction in oral squamous carcinoma cells
pp. 1699-1706(8)
Authors: Walker; Frei; Lawson

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Protein kinase C-associated kinase regulates NF-κB activation through inducing IKK activation
pp. 1707-1714(8)
Authors: Kim; Schifano; Oleksyn; Jordan; Ryan; Insel; Zhao; Chen

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Histone deacetylase inhibitors induce attenuation of Wnt signaling and TCF7L2 depletion in colorectal carcinoma cells
pp. 1715-1723(9)
Authors: Götze; Coersmeyer; Müller; Sievers

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Evaluation of meisoindigo, an indirubin derivative: in vitro antileukemic activity and in vivo pharmacokinetics
pp. 1724-1734(11)
Authors: Huang; Lin; Lee; Ho

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Ubiquitin-proteasomal degradation of antiapoptotic survivin facilitates induction of apoptosis in prostate cancer cells by pristimerin
pp. 1735-1741(7)
Authors: Liu; Gao; Deeb; Brigolin; Zhang; Shaw; Pindolia; Gautam

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Mechanisms and potential molecular markers of early response to combination epigenetic therapy in patients with myeloid malignancies
pp. 1742-1748(7)
Authors: Liu; Urbanavicius; Tan; Spencer; Dear

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Cytotoxic effects of pyrrolidine dithiocarbamate in small-cell lung cancer cells, alone and in combination with cisplatin
pp. 1749-1759(11)
Authors: Tahata; Yuan; Kikuchi; Takagi; Hirano; Toyoda

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Cadmium induces urokinase-type plasminogen activator receptor expression and the cell invasiveness of human gastric cancer cells via the ERK-1/2, NF-κB, and AP-1 signaling pathways
pp. 1760-1768(9)
Authors: Khoi; Xia; Lian; Kim; Kim; Joo; Chay; Kim; Jung

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Enhanced apoptosis by pemetrexed and simvastatin in malignant mesothelioma and lung cancer cells by reactive oxygen species-dependent mitochondrial dysfunction and Bim induction
pp. 1769-1777(9)
Authors: Hwang; Kim; Hwang; Kwon; Park; Cha; Kim; Yoon; Jeong; Kim

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