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The International Journal of Oncology provides an international forum for the publication of the latest, cutting-edge research in the broad area of oncology and cancer treatment. The journal accepts original high quality works and reviews on all aspects of oncology research including carcinogenesis, metastasis, epidemiology, chemotherapy and viral oncology. Through fair and efficient peer review, the journal is dedicated to publishing top tier research in the field, offering authors rapid publication as well as high standards of copy-editing and production. The International Journal of Oncology is published on a monthly basis in both print and early online.

Publisher: Spandidos Publications

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Volume 40, Number 5, 2012

Articles

Novel strategies in the treatment of castration-resistant prostate cancer (Review)
pp. 1313-1320(8)
Authors: Marech; Vacca; Ranieri; Gnoni; Dammacco

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MEDI3617, a human anti-Angiopoietin 2 monoclonal antibody, inhibits angiogenesis and tumor growth in human tumor xenograft models
pp. 1321-1330(10)
Authors: Leow; Coffman; Inigo; Breen; Czapiga; Soukharev; Gingles; Peterson; Fazenbaker; Woods; Jallal; Ricketts; Lavallee; Coats; Chang

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Improvement of replication fidelity by certain mesalazine derivatives
pp. 1331-1338(8)
Authors: Honeder, Clemens; Campregher, Christoph; Zens, Bettina; Scharl, Theresa; Gasche, Christoph

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ProstaCaid™ inhibits tumor growth in a xenograft model of human prostate cancer
pp. 1339-1344(6)
Authors: Jiang; Loganathan; Eliaz; Terry; Sandusky; Sliva

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Nestin as a novel therapeutic target for pancreatic cancer via tumor angiogenesis
pp. 1345-1357(13)
Authors: Yamahatsu, Kazuya; Matsuda, Yoko; Ishiwata, Toshiyuki; Uchida, Eiji; Naito, Zenya

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Crucial cross-talk of interleukin-1β and progesterone in human choriocarcinoma
pp. 1358-1364(7)
Authors: Zachariades; Mparmpakas; Thomas; Rand-Weaver; Karteris

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Pathway simulations in common oncogenic drivers of leukemic and rhabdomyosarcoma cells: A systems biology approach
pp. 1365-1390(26)
Authors: Lambrou; Zaravinos; Adamaki; Spandidos; Tzortzatou-Stathopoulou; Vlachopoulos

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Involvement of p21waf1/cip1 expression in the cytotoxicity of the potent histone deacetylase inhibitor spiruchostatin B towards susceptible NALM-6 human B cell leukemia cells
pp. 1391-1396(6)
Authors: Kanno, Syu-Ichi; Maeda, Naoyuki; Tomizawa, Ayako; Yomogida, Shin; Katoh, Tadashi; Ishikawa, Masaaki

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Expression profiles of Toll-like receptors in non-small cell lung cancer and idiopathic pulmonary fibrosis
pp. 1397-1404(8)
Authors: Samara, Katerina D.; Antoniou, Katerina M.; Karagiannis, Konstantinos; Margaritopoulos, Georgios; Lasithiotaki, Ismini; Koutala, Eleni; Siafakas, Nikolaos M.

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Upregulated expression of ADAM12 is associated with progression of oral squamous cell carcinoma
pp. 1414-1422(9)
Authors: Uehara; Shiiba; Shinozuka; Saito; Kouzu; Koike; Kasamatsu; Sakamoto; Ogawara; Uzawa; Tanzawa

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Hypoxia and TP53 deficiency for induced pluripotent stem cell-like properties in gastrointestinal cancer
pp. 1423-1430(8)
Authors: Hoshino, Hiromitsu; Nagano, Hiroaki; Haraguchi, Naotsugu; Nishikawa, Shimpei; Tomokuni, Akira; Kano, Yoshihiro; Fukusumi, Takahito; Saito, Toshiyuki; Ozaki, Miyuki; Sakai, Daisuke; Satoh, Taroh; Eguchi, Hidetoshi; Sekimoto, Mitsugu; Doki, Yuichiro; Mori, Masaki; Ishii, Hideshi

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Blockade of TRPM8 activity reduces the invasion potential of oral squamous carcinoma cell lines
pp. 1431-1440(10)
Authors: Okamoto, Yoshihiko; Ohkubo, Tsuyako; Ikebe, Tetsuro; Yamazaki, Jun

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Characterization of a novel mouse monoclonal antibody, clone 1E8.33, highly specific for human procollagen 11A1, a tumor-associated stromal component
pp. 1447-1454(8)
Authors: García-Ocaña; Vázquez; García-Pravia; Fuentes-Martínez; Menéndez-Rodríguez; Fresno-Forcelledo; Barneo-Serra; Del Amo-Iribarren; Simón-Buela; De Los Toyos

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Identification of genes potentially involved in bone metastasis by genome-wide gene expression profile analysis of non-small cell lung cancer in mice
pp. 1455-1469(15)
Authors: Dat, Le Tan; Matsuo, Taisuke; Yoshimaru, Tetsuro; Kakiuchi, Soji; Goto, Hisatsugu; Hanibuchi, Masaki; Kuramoto, Takuya; Nishioka, Yasuhiko; Sone, Saburo; Katagiri, Toyomasa

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Inhibition of cell viability by human IFN-β is mediated by microRNA-431
pp. 1470-1476(7)
Authors: Tanaka; Sugaya; Kita; Arai; Kanda; Fujii; Imazeki; Sugita; Yokosuka; Suzuki

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Down-regulation of miR-125a-3p in human gastric cancer and its clinicopathological significance
pp. 1477-1482(6)
Authors: Hashiguchi; Nishida; Mimori; Sudo; Tanaka; Shibata; Ishii; Mochizuki; Hase; Doki; Mori

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The anti-obesity drug orlistat promotes sensitivity to TRAIL by two different pathways in hormone-refractory prostate cancer cells
pp. 1483-1491(9)
Authors: Fujiwara, Jun; Sowa, Yoshihiro; Horinaka, Mano; Koyama, Makoto; Wakada, Miki; Miki, Tsuneharu; Sakai, Toshiyuki

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Personalized peptide vaccination in patients with refractory non-small cell lung cancer
pp. 1492-1500(9)
Authors: Yoshiyama; Terazaki; Matsueda; Shichijo; Noguchi; Yamada; Mine; Ioji; Itoh; Shirouzu; Sasada; Takamori

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Carboxyl-terminal modulator protein induces apoptosis by regulating mitochondrial function in lung cancer cells
pp. 1515-1524(10)
Authors: Hwang, Soon-Kyung; Minai-Tehrani, Arash; Yu, Kyeong-Nam; Chang, Seung-Hee; Kim, Ji-Eun; Lee, Kee-Ho; Park, Jongsun; Beck, George R.; Cho, Myung-Haing

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A novel CD44v6 targeting antibody fragment with improved tumor-to-blood ratio
pp. 1525-1532(8)
Authors: Sandström; Haylock; Spiegelberg; Qvarnström; Wester; Nestor

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miR-10b promotes cell invasion through RhoC-AKT signaling pathway by targeting HOXD10 in gastric cancer
pp. 1553-1560(8)
Authors: Liu, Zhuo; Zhu, Jiaming; Cao, Hong; Ren, Hui; Fang, Xuedong

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Expression analysis of Cdc42 in lung cancer and modulation of its expression by curcumin in lung cancer cell lines
pp. 1561-1568(8)
Authors: Chen, Qing-Yong; Jiao, De-Min; Yao, Qing-Hua; Yan, Jie; Song, Jia; Chen, Fang-Yuan; Lu, Guo-Hua; Zhou, Jian-Ying

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Yin Yang-1 inhibits tumor cell growth and inhibits p21WAF1/Cip1 complex formation with cdk4 and cyclin D1
pp. 1575-1580(6)
Authors: Ishii; Hulett; Li; Santiago; Parish; Khachigian

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Mucin production determines sensitivity to bortezomib and gemcitabine in pancreatic cancer cells
pp. 1581-1589(9)
Authors: Wissniowski; Meister; Hahn; Kalden; Voll; Ocker

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Identification of prognostic biomarkers for response to radiotherapy by DNA microarray in nasopharyngeal carcinoma patients
pp. 1590-1600(11)
Authors: Yang, Shu; Chen, Jiaxin; Guo, Yi; Lin, Hui; Zhang, Zheng; Feng, Guosheng; Hao, Yanrong; Cheng, Jinjian; Liang, Ping; Chen, Kehe; Wu, Hai; Li, Yao

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Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells
pp. 1619-1626(8)
Authors: Hsu, Andrew; Zhang, Wenliang; Lee, Jen-Fu; An, Jin; Ekambaram, Prasanna; Liu, Jingjing; Honn, Kenneth V.; Klinge, Carolyn M.; Lee, Menq-Jer

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The p85α regulatory subunit of PI3K mediates cAMP-PKA and retinoic acid biological effects on MCF7 cell growth and migration
pp. 1627-1635(9)
Authors: Donini; Di Zazzo; Zuchegna; Di Domenico; D'Inzeo; Nicolussi; Avvedimento; Coppa; Porcellini

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Aspirin enhances doxorubicin-induced apoptosis and reduces tumor growth in human hepatocellular carcinoma cells in vitro and in vivo
pp. 1636-1642(7)
Authors: Hossain; Kim; Jang; Kang; Yoon; Moon; Chung; Kim; Choi; Copple; Kim

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Targeting cysteine-mediated dimerization of the MUC1-C oncoprotein in human cancer cells
pp. 1643-1649(7)
Authors: Raina; Ahmad; Rajabi; Panchamoorthy; Kharbanda; Kufe

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Prognostic and diagnostic relevance of hypermethylated in cancer 1 (HIC1) CpG island methylation in renal cell carcinoma
pp. 1650-1658(9)
Authors: Eggers, H.; Steffens, S.; Grosshennig, A.; Becker, J. U.; Hennenlotter, J.; Stenzl, A.; Merseburger, A. S.; Kuczyk, M. A.; Serth, J.

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Heat shock protein 90 is a promising target for effective growth inhibition of gastrointestinal neuroendocrine tumors
pp. 1659-1667(9)
Authors: Gloesenkamp; Nitzsche; Lim; Normant; Vosburgh; Schrader; Ocker; Scherübl; Höpfner

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Protein interactions with HER-family receptors can have different characteristics depending on the hosting cell line
pp. 1677-1682(6)
Authors: Barta; Malmberg; Melicharova; Strandgård; Orlova; Tolmachev; Laznicek; Andersson

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Geraniol induces cooperative interaction of apoptosis and autophagy to elicit cell death in PC-3 prostate cancer cells
pp. 1683-1690(8)
Authors: Kim, Su-Hwa; Park, Eun-Jung; Lee, Chae Ryun; Chun, Jung Nyeo; Cho, Nam-Hyuk; Kim, In-Gyu; Lee, Sanghoon; Kim, Tae Woo; Park, Hyun Ho; So, Insuk; Jeon, Ju-Hong

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Sunitinib enhances antitumor effects against chemotherapy-resistant bladder cancer through suppression of ERK1/2 phosphorylation
pp. 1691-1696(6)
Authors: Takeuchi; Eto; Shiota; Tatsugami; Yokomizo; Kuroiwa; Itsumi; Naito

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Inhibition of migration and invasion of LNCaP human prostate carcinoma cells by cordycepin through inactivation of Akt
pp. 1697-1704(8)
Authors: Jeong, Jin-Woo; Jin, Cheng-Yun; Park, Cheol; Han, Min Ho; Kim, Gi-Young; Moon, Sung-Kwon; Kim, Chan Gil; Jeong, Yong Kee; Kim, Wun-Jae; Lee, Jae-Dong; Choi, Yung Hyun

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ADAM17 targets MMP-2 and MMP-9 via EGFR-MEK-ERK pathway activation to promote prostate cancer cell invasion
pp. 1714-1724(11)
Authors: Xiao; Lin; Lin; Liu; Qin; Zou; Guo; Liu; Wang; Yu

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