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MOLECULAR EVENTS IN THE INITIATION AND PROGRESSION OF BLADDER-CANCER (REVIEW)

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Bladder cancer is an excellent system in which to study molecular events in the initiation and progression of a malignancy. This review focuses on chemical carcinogenesis, cytogenetics, tumor suppressor genes, oncogenes, growth factors, and metastasis in bladder cancer. Where possible, the molecular information will be correlated with well described epidemiologic, pathologic, and clinical risk factors. Critical appraisal of some of the most recently described genetic changes is provided.

Document Type: Research Article

Publication date: 01 October 1993

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  • The International Journal of Oncology provides an international forum for the publication of the latest, cutting-edge research in the broad area of oncology and cancer treatment. The journal accepts original high quality works and reviews on all aspects of oncology research including carcinogenesis, metastasis, epidemiology, chemotherapy and viral oncology. Through fair and efficient peer review, the journal is dedicated to publishing top tier research in the field, offering authors rapid publication as well as high standards of copy-editing and production. The International Journal of Oncology is published on a monthly basis in both print and early online.
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