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Facing towards epidermal stem cells (Review)

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Skin contains somatic stem cells that generate keratinocyte, melanocyte and mesenchymal cell lineages. These somatic stem cells have traditionally been thought to be restricted in their differentiation and regeneration potential to the tissues in which they reside. This review focused on epidermal stem cells (ESCs). These cells are distinguished from transitory amplifier cells and post-mitotic cells. ESC are found in the interadnexal epidermis and in the bulge region of hair follicles. A series of ESCs markers are available, but increased sensitivity and specificity require further development.
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Document Type: Research Article

Affiliations: Department of Dermatopathology, University Hospital Sart Tilman, B-4000 Li├Ęge, Belgium

Publication date: January 1, 2010

More about this publication?
  • The International Journal of Molecular Medicine is a monthly, peer-reviewed journal devoted to the publication of high quality studies related to the molecular mechanisms of human disease. The journal welcomes research on all aspects of molecular and clinical research, ranging from biochemistry to immunology, pathology, genetics, human genomics, microbiology, molecular pathogenesis, molecular cardiology, molecular surgery and molecular psychology.

    The International Journal of Molecular Medicine aims to provide an insight for researchers within the community in regard to developing molecular tools and identifying molecular targets for the diagnosis and treatment of a diverse number of human diseases.
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