Infection with Helicobacter pylori (HP) has an unknown prevalence in several Romanian regions. Recent data are missing. The aim of this study was to estimate the prevalence of dyspepsia in the NorthWest part of Romania and to analyze the epidemiological trends of HP infection prevalence
in a symptomatic population in this region by comparing with previous published data. Our study population consisted of 414 patients: 264 female (63.8%) and 150 male (36.2%), mean age 45.89±17.24 years (range, 697 years) who attended a single
secondary center in Zalau, Salaj, NorthWest Romania, between 2014 and 2018 for dyspeptic symptoms, either by their own initiative or by referral from their general practitioner. Testing was performed by IgG antiHP assessment G antiHP antibodies were found in 169 individuals (40.8%).
In females, the prevalence of HP infection was 40.53% (107/264) and in males 41.35% (62/150). There was a higher prevalence of positive antibodies in the rural areas compared with urban areas (42.29 vs. 39.75%). In conclusion, the prevalence of HP infection is 40.8%, without
sex differences in dyspeptic patients from a representative population in NorthWestern Romania and the prevalence increases with age. Comparing our results with those of previous studies on the prevalence of HP infection from the same region, we were able to signal a decline in prevalence
in HP infection over a 30-year interval.
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Document Type: Research Article
Second Medical Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400006 ClujNapoca, Romania
Central Laboratory, Salvosan Ciobanca Medical Center, 450112 Zalau, Romania
Department of Informatics, Iuliu Hatieganu University of Medicine and Pharmacy, 400006 ClujNapoca, Romania
October 1, 2020
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Experimental and Therapeutic Medicine aims to ensure the expedient publication, in both print and electronic format, of studies relating to biology, gene therapy, infectious disease, microbiology, molecular cardiology and molecular surgery. The journal welcomes studies pertaining to all aspects of molecular medicine, and studies relating to in vitro or in vivo experimental model systems relevant to the mechanisms of disease are also included.
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