@article {Sun:2019:1792-0981:404,
title = "A casecontrol study of the relationship between visceral fat and development of uterine fibroids",
journal = "Experimental and Therapeutic Medicine",
parent_itemid = "infobike://sp/etm",
publishercode ="sp",
year = "2019",
volume = "18",
number = "1",
publication date ="2019-01-01T00:00:00",
pages = "404-410",
itemtype = "ARTICLE",
issn = "1792-0981",
eissn = "1792-1015",
url = "https://www.ingentaconnect.com/content/sp/etm/2019/00000018/00000001/art00050",
doi = "doi:10.3892/etm.2019.7575",
author = "Sun and Xie and Zhao and Li",
abstract = "Relationship between visceral fat and development of uterine fibroids in adult women was investigated. A total of 89patients with uterine fibroids treated in the First Hospital of Hebei Medical University from April2016 to April2018 were enrolled. Another 81healthy
women without uterine fibroids receiving physical examination in the same period were selected as the control group. Selfdesigned questionnaires were used to investigate the general conditions of the subjects, bioelectrical impedance analysis was employed to analyze obesityrelated indicators,
and their correlation with the risk of uterine fibroids was explored. Visceral fat area (VFA), body mass index (BMI), body fat percentage, waist circumference, waistheight ratio and waisthip ratio were positively correlated with the incidence rate of uterine fibroids, and the odds ratio (OR),
95%confidence interval (CI) was 3.910 (2.029, 7.536), 2.716 (1.444, 5.110), 4.335 (1.507, 12.469), 2.881 (1.531, 5.423), 3.837 (1.914, 7.692) and 7.707 (3.501, 16.965), respectively. VFA and body fat percentage were correlated with the size of uterine fibroids, but the correlations were
relatively weak. With the increase in the VFA, BMI, waist circumference, waistheight ratio, and waisthip ratio, the risk of uterine fibroids was elevated. The BMI, VFA and waist circumference of patients with uterine fibroids were gradually increased with increasing age, showing statistically
significant differences. Increased body fat (especially abdominal visceral fat) is able to enhance the risk of uterine fibroids. For perimenopausal women, the waisthip ratio measured can be used as an indicator screening highrisk groups of uterine fibroids. This method is simple, easy and
inexpensive. At the same time, providing nutrition guidance and changing diet and exercise habits are important measures to prevent the development of uterine fibroids.",
}