Relationship between visceral fat and development of uterine fibroids in adult women was investigated. A total of 89 patients with uterine fibroids treated in the First Hospital of Hebei Medical University from April 2016 to April 2018 were enrolled. Another 81 healthy
women without uterine fibroids receiving physical examination in the same period were selected as the control group. Selfdesigned questionnaires were used to investigate the general conditions of the subjects, bioelectrical impedance analysis was employed to analyze obesityrelated indicators,
and their correlation with the risk of uterine fibroids was explored. Visceral fat area (VFA), body mass index (BMI), body fat percentage, waist circumference, waistheight ratio and waisthip ratio were positively correlated with the incidence rate of uterine fibroids, and the odds ratio (OR),
95% confidence interval (CI) was 3.910 (2.029, 7.536), 2.716 (1.444, 5.110), 4.335 (1.507, 12.469), 2.881 (1.531, 5.423), 3.837 (1.914, 7.692) and 7.707 (3.501, 16.965), respectively. VFA and body fat percentage were correlated with the size of uterine fibroids, but the correlations were
relatively weak. With the increase in the VFA, BMI, waist circumference, waistheight ratio, and waisthip ratio, the risk of uterine fibroids was elevated. The BMI, VFA and waist circumference of patients with uterine fibroids were gradually increased with increasing age, showing statistically
significant differences. Increased body fat (especially abdominal visceral fat) is able to enhance the risk of uterine fibroids. For perimenopausal women, the waisthip ratio measured can be used as an indicator screening highrisk groups of uterine fibroids. This method is simple, easy and
inexpensive. At the same time, providing nutrition guidance and changing diet and exercise habits are important measures to prevent the development of uterine fibroids.
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Document Type: Research Article
Department of Nursing, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, P.R. China
Department of Nutrition, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, P.R. China
Department of Gynecology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, P.R. China
Publication date: January 1, 2019
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Experimental and Therapeutic Medicine aims to ensure the expedient publication, in both print and electronic format, of studies relating to biology, gene therapy, infectious disease, microbiology, molecular cardiology and molecular surgery. The journal welcomes studies pertaining to all aspects of molecular medicine, and studies relating to in vitro or in vivo experimental model systems relevant to the mechanisms of disease are also included.
All materials submitted to this journal undergo the appropriate review via referees who are experts in this field. All materials submitted follow international guidelines with regard to approval of experiments on humans and animals.
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