Skip to main content

Open Access Elucidation of local inflammatory response and role of physiologically active lipids – post-surgical and neuropathic pain

Everyone understands the concept of pain, of how it registers as the personal experience of harm in one's own body. However, despite the near-universal appreciation for pain and its effects, surprisingly little is known about the mechanisms behind it. Dr Nobuko Ito, based in the Department of Anesthesiology and Pain Relief Center at the University of Tokyo, explains how, for instance, neuropathic pain, is often a result of disorders of the peripheral nervous system or the central nervous system. 'This can manifest as abnormal sensations, known as dysesthesia, or pain from stimuli that would ordinarily be harmless, known as allodynia.' From her perspective, the treatment of neuropathic pain can be extremely difficult because the pain mechanisms are not fully understood. In response to this, Ito has been conducting investigations to elucidate understanding, and one exciting avenue of study is lipids. A lipid is a biomolecule that is responsible for a variety of biological functions and is essential for life activity.


Document Type: Research Article

Publication date: August 1, 2019

More about this publication?
  • Impact is a series of high-quality, open access and free to access science reports designed to enable the dissemination of research impact to key stakeholders. Communicating the impact and relevance of research projects across a large number of subjects in a content format that is easily accessible by an academic and stakeholder audience. The publication features content from the world's leading research councils, policy groups, universities and research projects. Impact is published under a CC-BY Creative Commons licence.

  • Subscribe to this Title
  • Terms & Conditions
  • Disseminating research in Impact
  • Information about Impact
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content