Skip to main content
padlock icon - secure page this page is secure

Open Access Longitudinal epidemiological studies to clarify the difference in effectiveness of countermeasures against influenza in different age groups

Download Article:
 Download
(PDF 341.7 kb)
 
Uchida and the research team are working to clarify the differences in influenza epidemics in different age groups, with a view to more effectively preventing and treating outbreaks; thereby filling a gap in the research landscape. Their research is specifically targeted to Japan, where influenza poses a problem: 'In Japan, influenza is prevalent almost every winter,' Uchida explains. 'Although the exact number of people infected is not clear, the National Institute of Infectious Diseases Japan estimates that more than 10 million people are infected. Influenza not only presents a burden on medical care, it also leads to the problem of increasing the excess death of the elderly and stagnating social economy.' Vaccination is an effective preventative measure, ie. pharmaceutical intervention (PI), along with mask wearing and school closure, ie. non-pharmaceutical intervention (NPI). However, evidence of these NPIs is lacking and medical diagnosis and administration of antiviral drugs are required at the early stage of influenza onset, but sometimes it is too late and infection has already begun. Therefore, there is work to be done. Uchida explains why the true effectiveness of current PIs and NPIs has not been evaluated: 'Influenza vaccine is sometimes expressed as incomplete. This is because influenza subtypes change every year and their effects are not fully demonstrated if they differ from the type used for vaccination. There are also years when vaccines run short because vaccine production does not keep up with the size of the epidemic,' he says. 'In addition, the vaccine is about $30 in Japan, so it is not inexpensive. Therefore, citizens who doubt the effect of the influenza vaccine influence the decrease of vaccine coverage and are also becoming part of the cause of epidemic expansion. Furthermore, since the effect of NPI is difficult to quantify, no standard consensus has been obtained and the effect varies depending on the research announcement.' It is the team's goal to quantify the effectiveness of PIs and NPIs as much as possible, as they are confident that if this can be done, countering influenza will become easier. To do this, the researchers are using epidemiological methods in their work.
No References for this article.
No Supplementary Data.
No Article Media
No Metrics

Keywords: DECREASE OF VACCINE COVERAGE; EPIDEMIC EXPANSION; EPIDEMIOLOGICAL METHODS; INFLUENZA EPIDEMICS; INFLUENZA VACCINE; NON-PHARMACEUTICAL INTERVENTION (NPI); PHARMACEUTICAL INTERVENTION (PI); PREVENTING AND TREATING OUTBREAKS; VACCINATION

Document Type: Research Article

Affiliations: Gunma University, Japan

Publication date: April 1, 2019

More about this publication?
  • Impact is a series of high-quality, open access and free to access science reports designed to enable the dissemination of research impact to key stakeholders. Communicating the impact and relevance of research projects across a large number of subjects in a content format that is easily accessible by an academic and stakeholder audience. The publication features content from the world's leading research councils, policy groups, universities and research projects. Impact is published under a CC-BY Creative Commons licence.

  • Subscribe to this Title
  • Terms & Conditions
  • Disseminating research in Impact
  • Information about Impact
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more