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Open Access A novel new method for identification of bacteria outpaces sepsis

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Infectious diseases represent a significant cause of mortality across the world in both developed and developing countries. Sepsis is one such disease that presents everywhere. It causes between six and nine million deaths a year globally, representing a significant cause of death across the world. Sepsis often requires intensive care over several weeks so even when a full recovery is made, the costs are huge to both the individual and the health system. However, it is chronically underestimated as an issue worldwide. Treatment of sepsis requires administration of appropriate antibiotics as early as possible. However, broad-spectrum antibiotics are administered at the hospitals until the infecting bacterial species is identified. This is because current identification methods rely on the time-consuming blood culture. A novel 'Tm Mapping method' has been developed to identify the bacterial species in about three hours without the need for blood culture.
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Keywords: 16S RDNA GENE; ANTIBIOTIC-RESISTANT BACTERIA; BLOOD CULTURE; BROAD-SPECTRUM ANTIBIOTICS; CAUSATIVE BACTERIA; CLOSTRIDIUM DIFFICILE; DIAGNOSIS OF INFECTIOUS DISEASES; DIAGNOSTIC SYSTEM; DNA POLYMERASE; GENETIC STRUCTURE; IDENTIFICATION OF BACTERIA; INFECTIOUS DISEASE; MELTING TEMPERATURE MAPPING METHOD; NEW DIAGNOSTIC TECHNIQUES; PCR; POLYMERASE CHAIN REACTION; SECONDARY INFECTION; SEPSIS; TM MAPPING METHOD

Document Type: Research Article

Publication date: December 1, 2018

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