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Open Access Developing a 3D quantitative method of dopamine transporter SPECT

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Toyama and Ichihara hope to strengthen our understanding of how dopamine is transported and absorbed within the brain and provide a deeper awareness of what exactly goes wrong when Parkinson's disease takes hold. Furthermore, this research can help distinguish between Parkinson's disease and the broader Parkinson syndrome, thereby aiding in the development of more specialised diagnoses and treatments. Within the striatum, there are two groups of neurons called the caudate nucleus and the putamen. These areas are of particular interest to Toyama and Ichihara. 'If we can accurately discriminate the dopamine uptakes of the caudate nucleus and putamen on the striatum by quantitative measurement, differential diagnosis between Parkinson's disease and syndrome might become possible,' Toyama describes.
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Keywords: 3D PRINTER; BIOMARKER; CAUDATE NUCLEUS; DEGENERATIVE MOVEMENT DISORDERS; DOPAMINE; DOPAMINERGIC SPECT TRACERS; MUSCLE MOVEMENT; NEURODEGENERATIVE SYNDROMES; PARKINSON SYNDROME; PARKINSON'S DISEASE; PRE-SYNAPTIC TERMINAL; PUTAMEN; QUANTITATIVE (123I) FP-CIT SPECT SCANNING; SPECT IMAGING; STRIATUM

Document Type: Research Article

Publication date: December 1, 2018

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