Modernising Medical Microbiology
These include: the Comprehensive Resistance Prediction for Tuberculosis: an International Consortium (CRyPTIC) project, which is seeking to speed up diagnosis of tuberculosis (TB); the environmental REsistome: confluence of Human and Animal Biota in antibiotic resistance spread (REHAB), which is looking in detail on a genetic level at bacteria in farm animals, human/animal sewage, sewage treatment works and rivers, to work out the complex network of transmission of important antibiotic-resistant bacteria and antibiotic resistance genes; Infections in Oxfordshire Research Database (IORD), which is seeking to improve the management of infection in UK hospitals; Antibiotic Reduction & Konservation (ARK) Programme, which is aiming to safely reduce antibiotic use in hospitals; National Institute of Health Research (NIHR) Health Protection Research Unit, which is developing new ways to detect, monitor, investigate and reduce the occurrence of healthcare-associated infections and antimicrobial resistance in the NHS; Health Innovation Challenge Fund (HICF), which is working to demonstrate locally-based genome sequencing operating in a network of routine UK NHS service laboratories at Oxford, Brighton, Birmingham and Leeds; whole-genome association studies that are attempting to try and pin down genetic variants associated with phenotypes such as increased virulence or mortality in various study species; and the MMM Transmission Study, which is the group's very first project that is using a bug's genetic code to work out whether and how it is being passed from person to person.
Keywords: ANTIBIOTIC RESISTANCE GENES; ANTIBIOTIC RESISTANCE SPREAD; ANTIMICROBIAL RESISTANCE; GENOME SEQUENCING; INFECTIONS; MEDICAL MICROBIOLOGY; OCCURRENCE OF HEALTHCARE-ASSOCIATED INFECTIONS; RESISTANCE PREDICTION FOR TUBERCULOSIS; TRANSMISSION OF ANTIBIOTIC-RESISTANT BACTERIA; WHOLE-GENOME ASSOCIATION
Document Type: Research Article
Publication date: 01 March 2018
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