Elucidation of the molecular mechanism of disease development due to calpain dysfunction – CALPAIN
In an effort to further scientific understanding of calpains and their vital biological roles, the CALPAIN project was established within the Tokyo Metropolitan Institute of Medical Science in Japan. Led by Department Head Dr Hiroyuki Sorimachi, the CALPAIN project's goals include analysing the mechanisms of calpains at a molecular level; clarifying their physiological functions; analysing diseases marked by calpain deficiency using genetically-modified mice; and developing future diagnosis and treatment plans for calpain-related diseases.
Document Type: Research Article
Publication date: March 1, 2018
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