Skip to main content
padlock icon - secure page this page is secure

Open Access Innovations in mass spectrometry imaging (MSI) to identify the underlying mechanisms in biological systems

Download Article:
 Download
(PDF 307 kb)
 
Using the latest innovations in mass spectrometry imaging (MSI) to identify the underlying mechanisms in biological systems is proving to be a powerful tool in disease and food characterisation. Professor Nobuhiro Zaima believes it will help define the future of cellular investigation.

Mass spectrometry imaging (MSI) is a well-understood technique used in chemical mass spectrometry to visualise the spatial distribution of chemical compositions including biomarkers, metabolites, peptides and proteins, by their molecular mass. Although widely used traditional methodologies such as radiochemistry and immunohistochemistry achieve the same goal as MSI, they are limited in their abilities to analyse multiple samples at once, and can prove to be lacking if researchers do not have prior knowledge of the samples being studied. MSI offers a much-improved scope to examine the actual building blocks of many common chemical processes, and expand our knowledge of their operations, and why sometimes they fail. MALDI is an emerging technology based on the principles of MSI, yet MALDI imaging is becoming an even more powerful tool.
No References for this article.
No Supplementary Data.
No Article Media
No Metrics

Keywords: ABDOMINAL AORTIC ANEURYSM; BIOMARKERS; CHEMICAL COMPOSITIONS; DISEASE; FOOD CHARACTERISATION; MALDI IMAGING; MASS SPECTROMETRY IMAGING (MSI); METABOLITES; PEPTIDES AND PROTEINS; TGCV

Document Type: Research Article

Publication date: March 1, 2018

More about this publication?
  • Impact is a series of high-quality, open access and free to access science reports designed to enable the dissemination of research impact to key stakeholders. Communicating the impact and relevance of research projects across a large number of subjects in a content format that is easily accessible by an academic and stakeholder audience. The publication features content from the world's leading research councils, policy groups, universities and research projects. Impact is published under a CC-BY Creative Commons licence.

  • Subscribe to this Title
  • Terms & Conditions
  • Disseminating research in Impact
  • Information about Impact
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more