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Open Access Artificial Organelles: Reactions inside Protein–Polymer Supramolecular Assemblies

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Reactions inside confined compartments at the nanoscale represent an essential step in the development of complex multifunctional systems to serve as molecular factories. In this respect, the biomimetic approach of combining biomolecules (proteins, enzymes, mimics) with synthetic membranes is an elegant way to create functional nanoreactors, or even simple artificial organelles, that function inside cells after uptake. Functionality is provided by the specificity of the biomolecule(s), whilst the synthetic compartment provides mechanical stability and robustness. The availability of a large variety of biomolecules and synthetic membranes allows the properties and functionality of these reaction spaces to be tailored and adjusted for building complex self-organized systems as the basis for molecular factories.
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Keywords: AMPHIPHILIC COPOLYMERS; ARTIFICIAL ORGANELLES; ENZYMATIC REACTIONS; NANOREACTORS

Document Type: Research Article

Affiliations: 1: University of Basel, Department of Chemistry, Klingelbergstrasse 80, CH-4056 Basel, Switzerland 2: University of Basel, Department of Chemistry, Klingelbergstrasse 80, CH-4056 Basel, Switzerland. [email protected] 3: University of Basel, Department of Chemistry, Klingelbergstrasse 80, CH-4056 Basel, Switzerland. [email protected]

Publication date: June 1, 2016

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  • International Journal for Chemistry and Official Membership Journal of the Swiss Chemical Society (SCS) and its Divisions

    CHIMIA, a scientific journal for chemistry in the broadest sense, is published 10 times a year and covers the interests of a wide and diverse readership. Contributions from all fields of chemistry and related areas are considered for publication in the form of Review Articles and Notes. A characteristic feature of CHIMIA are the thematic issues, each devoted to an area of great current significance.

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