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Open Access The Changing Face of Organic Synthesis

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The article describes the content of the Paul Karrer Lecture given at the University of Z├╝rich on the 20th of June 2007 by Professor Steven V. Ley. The lecture illustrates the work underway within the Chemistry Department at Cambridge to develop microreactors for flow chemistry applications. These modular, small footprint devices are capable of preparing a wide range of compounds including natural products in up to seven synthesis steps. Products can generally be obtained in high yield and purity without conventional work-up methods using a variety of reaction mixer chips and pre-packed flow tubes of immobilised reagents and scavengers.

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Keywords: FLOW-MODE SYNTHESIS; MICROREACTORS

Document Type: Research Article

Publication date: 01 March 2008

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  • International Journal for Chemistry and Official Membership Journal of the Swiss Chemical Society (SCS) and its Divisions

    CHIMIA, a scientific journal for chemistry in the broadest sense, is published 10 times a year and covers the interests of a wide and diverse readership. Contributions from all fields of chemistry and related areas are considered for publication in the form of Review Articles and Notes. A characteristic feature of CHIMIA are the thematic issues, each devoted to an area of great current significance.

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