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International Journal for Chemistry and Official Membership Journal of the Swiss Chemical Society (SCS) and its Divisions

CHIMIA, a scientific journal for chemistry in the broadest sense, is published 10 times a year and covers the interests of a wide and diverse readership. Contributions from all fields of chemistry and related areas are considered for publication in the form of Review Articles and Notes. A characteristic feature of CHIMIA are the thematic issues, each devoted to an area of great current significance.

Publisher: Swiss Chemical Society

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Volume 60, Number 9, September 2006
Process Chemistry

Editorial

Open Access Process Chemistry in API Development
pp. 516-517(2)
Authors: Marti, Hans-Ruedi; Siegel, Jay S.

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Articles

Open Access Early Process Development: The Wyeth Approach
pp. 518-522(5)
Authors: O'Brien, Michael K.; Kolb, Michael; Sutherland, Karen; McCoy, Kevin; Pilcher, Anthony

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Open Access Process Development for Active Pharmaceutical Ingredients Following a Developmental Cascade
pp. 523-529(7)
Authors: Adler, Carmen; Brunner, Jürg; Fichtner, Claudia; Küng, Peter; Levis, Michael K.; Ruchti, Hans-Rudolf; Sjöberg, Anders; Weber, Beat

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Open Access Process Development and Production Concepts for the Manufacturing of Organic Fine Chemicals at LONZA
pp. 530-533(4)
Authors: Heckmann, Golo; Previdoli, Felix; Riedel, Thomas; Ruppen, David; Veghini, Dario; Zacher, Uwe

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Open Access Process Research and Scale-up of the κ-Opioid Receptor Agonist CJ-15,161 Drug Candidate
pp. 554-560(7)
Authors: Andresen, Brian M.; Caron, Stéphane; Couturier, Michel; DeVries, Keith M.; Do, Nga M.; Dupont-Gaudet, Kristina; Ghosh, Arun; Girardin, Melina; Hawkins, Joel M.; Makowski, Teresa M.; Riou, Maxime; Sieser, Janice E.; Tucker, John L.; Vanderplas, Brian C.; Watson, Timothy J.N.

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Open Access With Asymmetric Hydrogenation Towards a New, Enantioselective Synthesis of Orlistat
pp. 561-565(5)
Authors: Birk, Rolf; Karpf, Martin; Püntener, Kurt; Scalone, Michelangelo; Schwindt, Mark; Zutter, Ulrich

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Open Access The Formation of a Crystalline Oxazolidin-5-one from (L)-Alanine and its Use as a Chiral Template in the Practical Synthesis of α-Substituted Alanine Esters
pp. 566-573(8)
Authors: Eriksson, Magnus; Napolitano, Elio; Xu, Jinghua; Kapadia, Suresh; Byrne, Denis; Nummy, Laurence; Grinberg, Nelu; Shen, Sherri; Lee, Heewon; Farina, Vittorio

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Open Access Recent Optimization Highlights of the Georgywood Process
pp. 574-579(6)
Authors: Barras, Jean-Pierre; Bourdin, Bernadette; Schröder, Fridtjof

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Open Access The Chemical Development of CHIR-258
pp. 584-592(9)
Authors: Zhu, Shuguang; Harwood, Eric; Cai, Shaopei; Shang, Xiao; Galvin, Gabriel; Jin, Li; Yeung, Arthur; Diaz, Brian; Zheng, Minna; Ryckman, David

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Open Access An Improved Process for Repaglinide via an Efficient and One Pot Process of (1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butan-1-amine – A Useful Intermediate
pp. 593-597(5)
Authors: Kolla, Naveenkumar; Elati, Chandrashekar R.; Vankawala, Pravinchandra J.; Gangula, Srinivas; Sajja, Eswaraiah; Anjaneyulu, Yerremilli; Bhattacharya, Apurba; Sundaram, Venkataraman; Mathad, Vijayavitthal T.

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Open Access Data-Oriented Process Development: Determination of Reaction Parameters by Small-Scale Calorimetry with in situ Spectroscopy
pp. 605-610(6)
Authors: Puxty, Graeme; Fischer, Ulrich; Jecklin, Marc; Hungerbühler, Konrad

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Open Access Cost Analysis of a Commercial Manufacturing Process of a Fine Chemical Compound Using Micro Process Engineering
pp. 611-617(7)
Authors: Krtschil, Ulrich; Hessel, Volker; Kralisch, Dana; Kreisel, Günther; Küpper, Michael; Schenk, Rainer

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Open Access Continuous Chemistry in Microreaction Systems for Practical Use
pp. 618-622(5)
Authors: Müller, Gernot; Gaupp, Theo; Wahl, Fabian; Wille, Gregor

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Open Access Process Research in the Ivory Tower
pp. 628-630(3)
Author: Finney, Nathaniel S.

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Highlights of Analytical Chemistry in Switzerland

Open Access Using Bacteria to Quantify Arsenic Contamination in Potable Water
pp. 631-631(1)
Authors: Van Der Meer, Jan Roelof; Berg, Michael; Trang, Pham Thi Kim

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Chimia-Report

Open Access Chimia-Report
pp. 636-641(6)

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