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International Journal for Chemistry and Official Membership Journal of the Swiss Chemical Society (SCS) and its Divisions

CHIMIA, a scientific journal for chemistry in the broadest sense, is published 10 times a year and covers the interests of a wide and diverse readership. Contributions from all fields of chemistry and related areas are considered for publication in the form of Review Articles and Notes. A characteristic feature of CHIMIA are the thematic issues, each devoted to an area of great current significance.

Publisher: Swiss Chemical Society

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Volume 50, Number 11, November 1996

Leading Articles

Open Access Sciences towards the Medicine of Tomorrow
pp. 507-510(4)
Author: Drews, Jürgen

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Open Access The Role of Genomics in Modern Drug Discovery
pp. 511-514(4)
Author: Steinmetz, Michael

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Open Access Roche Pharma Research from the Past to the Present
pp. 514-518(5)
Authors: Gwinner, Eckart; Carbonare, Bruno Dalle

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Pharma Division

Open Access The Discovery of Nonpeptide Endothelin Receptor Antagonists. Progression towards Bosentan
pp. 519-524(6)
Authors: Neidhart, Werner; Breu, Volker; Bur, Daniel; Burri, Kaspar; Clozel, Martine; Hirth, Georges; Müller, Marcel; Wessel, Hans P.; Ramuz, Henri

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Open Access Novel Solution- and Solid-Phase Strategies for the Parallel and Combinatorial Synthesis of Small-Molecular-Weight Compound Libraries
pp. 525-530(6)
Authors: Chucholowski, Alexander; Masquelin, Thierry; Obrecht, Daniel; Stadlwieser, Josef; Villaigordo, José M.

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Open Access Total Synthesis of Enantiomerically Pure (−)-Balanol
pp. 530-532(3)
Authors: Barbier, Pierre; Stadlwieser, Josef

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Open Access Synthesis of the HIV-Proteinase Inhibitor Saquinavir: A Challenge for Process Research
pp. 532-537(6)
Authors: Göbring, Wolfgang; Gokbale, Surendra; Hilpert, Hans; Roessler, Felix; Schlageter, Markus; Vogt, Peter

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Open Access Development of a Process to Prepare 2-Cyanopyrimidine on Commercial Scale
pp. 538-543(6)
Authors: Göhring, Wolfgang; Schildknecht, Jürg; Federspiel, Muriel

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Open Access Die Produktion von Wirkstoffen bei Roche; gestern, heute, morgen
pp. 544-554(11)
Authors: Jermann, Benno; Müller, Stefan

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Vitamin Division

Open Access Vitamin Tech Center: Scale-up als Herausforderung
pp. 555-558(4)
Author: Hugentobler, Max

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Open Access Stereoisomers of Tocopherols – Syntheses and Analytics
pp. 563-567(5)
Author: Netscher, Thomas

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Nachruf

Open Access Zum Gedenken an Professor Tadeus Reichstein
pp. 568-569(2)
Author: Tamm, Christoph

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EI - INFO - IS

Open Access Brennstoffzellen als Beispiel für den Technologietransfer am TWI
pp. 570-572(3)
Authors: Bührer, Heiner G.; Winzeler, Heinz B.

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Chimia-Report

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