There is sparse information on how treatments for erectile dysfunction (ED) affects couples. This study investigated the effects of ED treatments on 100 heterosexual couples' sexual functioning and whether function achieved using a short-acting versus a long-acting ED medication differed
significantly. Couples were randomized to use tadalafil or sildenafil for each of two 12-week study phases; they completed questionnaires (International Index of Sexual Function and Female Sexual Function Index) and kept sexual event diaries. All participants experienced significant improvements
over baseline sexual functioning, while the men used short- or long-acting ED medications with no significant differences related to the duration of drug action recorded for either the men or women. Despite this lack of difference in efficacy there was a strong preference by women (79%) and
their partners (16%) for the longer-acting medication. The reasons for this warrant further investigation. Understanding the effects on couples of the use of ED medications is a necessary aspect of ensuring ongoing sexual satisfaction in couples treated for ED.
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Female Sexual Function Index;
International Index of Erectile Function;
phosphodiesterase type 5 inhibitors;
Document Type: Research Article
Deakin University, Melbourne, Australia
Accident Research Centre, Monash University, Melbourne, Australia
Waikato Clinical School, Faculty of Medical & Health Sciences, University of Auckland, Hamilton, New Zealand
Publication date: August 1, 2009
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