Skip to main content
padlock icon - secure page this page is secure

Evaluating two group programmes of cognitive training in mild-to-moderate AD: Is there any difference between a ‘global' stimulation and a ‘cognitive-specific' one?

Buy Article:

$53.00 + tax (Refund Policy)

This study evaluated the efficacy of two different group procedures of non-pharmacological treatment in mild-to-moderate Alzheimer's disease (AD). Thirty-two patients entered the study and were divided in groups of four subjects. We compared recreational activities (‘global' stimulation) with a combination of procedural memory training on activities of daily living and neuropsychological rehabilitation of ‘residual' functions (‘cognitive-specific'). All patients and caregivers were ensured psychological support. Both group treatments were delivered for six weeks. Multidimensional efficacy assessment of functional, behavioural and neuropsychological aspects was performed. Patients receiving ‘global' stimulation showed a substantial reduction in behavioural disturbances (Neuropsychiatric Inventory [NPI]: frequency p =0.034; severity p =0.012); Revised Memory Behaviour Problems Checklist (frequency p =0.008; reaction p =0.027), and better performance in the Functional Living Skills Assessment (FLSA), a standardized direct measure of performance in everyday life ( p =0.021) and Verbal Fluency for Letters ( p =0.000). Patients receiving ‘cognitive-specific' treatment improved only on the scale evaluating functional competence in daily living (Nurses' Observation Scale for Geriatric Patients [NOSGER] p =0.018). At follow-up (six months later), compared with baseline, patients following the ‘global' stimulation treatment showed an improvement at caregiver distress on NPI ( p =0.04). No other significant difference was detected. Our results support the contention that a ‘global' treatment can lead to a significant improvement in AD patients, both for behavioural and functional aspects. The ‘cognitive-specific' treatment we used in this research did not show better efficacy.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics

Document Type: Research Article

Affiliations: 1: Neurorehabilitation Unit, IRCCS Don Gnocchi Foundation 2: Psychology Laboratory, Istituto Auxologico Italiano di Piancavallo (VB) & Psychology Department, University of Trieste, Trieste, Italy 3: Neurology Unit, Luigi Sacco Hospital, University of Milan, Milan

Publication date: May 1, 2006

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more