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Home / GAIA - Ecological Perspectives for Science and Society, Volume 33, Number 1

Open Access Putting gene drives into context: Risks, depth of intervention, and regulatory challenges

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Engineered gene drives are an emerging technology for the large-scale genetic modification of natural populations of species. They are controversial due to high levels of uncertainty about their risks and benefits. We analyze gene drives in their social, natural, and technological contexts. We discuss their depth of intervention and compare gene drives to “conventional” genetic modification techniques and to other novel high-impact technologies. While gene drives might overpromise and under-deliver solutions for problems of sustainable development, they also represent a paradigm shift in human technological interference with nature, thus requiring broad discussion in society.

Keywords: biotechnology; ethics; gene drives; governance; risk assessment

Document Type: Discussion

Publication date: May 1, 2024

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